Aciclovir and Valaciclovir Dosage Options
Standard Aciclovir Tablet Dosages
Aciclovir 400mg tablets represent the most commonly prescribed strength for treating cold sores in the UK. The typical dosing regimen involves taking 400mg five times daily for five days, starting as soon as symptoms appear. Some patients may be prescribed 200mg tablets, taken five times daily, though the 400mg strength offers greater convenience with the same therapeutic effect.
Valaciclovir Alternative Dosing
Valaciclovir 500mg tablets provide an alternative antiviral option, often preferred for their simplified dosing schedule. The standard regimen is 500mg twice daily for five days. Valaciclovir converts to aciclovir in the body but offers improved absorption, allowing for less frequent dosing whilst maintaining effectiveness against herpes simplex virus.
EverydayMeds Treatment Options
Through EverydayMeds, patients can access both aciclovir 400mg tablets and valaciclovir 500mg tablets following appropriate consultation. Our online pharmacy also stocks branded options including Valtrex 500mg tablets. For those preferring topical treatment, aciclovir 5% cream provides localised antiviral action, though tablets generally offer superior therapeutic outcomes for recurrent cold sores.
Dosage Timing and Effectiveness
The effectiveness of both aciclovir and valaciclovir depends significantly on treatment timing. Starting antiviral tablets during the prodromal stage - when tingling, itching, or burning sensations first appear - can reduce outbreak duration by 1-2 days. Delayed treatment initiation, after blisters have formed, may provide limited benefit. Patients experiencing frequent outbreaks may benefit from suppressive therapy using modified dosing regimens.
Special Considerations
Dosage adjustments may be necessary for patients with kidney impairment, as both medications are primarily eliminated through renal excretion. Elderly patients or those taking concurrent medications should discuss appropriate dosing with healthcare providers. EverydayMeds ensures all prescriptions are clinically reviewed before dispensing, providing additional safety oversight for cold sore treatments.






