BNF Sildenafil vs Spedra: Effectiveness Compared

When choosing between BNF-listed ED treatments, sildenafil and Spedra (avanafil) are both proven options with different profiles. Sildenafil, available as both branded Viagra and generic versions, has been treating erectile dysfunction for over 25 years. Spedra is a newer medication with potentially faster onset. Understanding their differences helps you make an informed choice about which treatment may suit your needs better.

  • Sildenafil typically starts working within 30-60 minutes and effects last 4-6 hours
  • Spedra may work faster (15-30 minutes) but duration is similar at 4-6 hours
  • Generic sildenafil offers significant cost savings compared to branded options
  • Both require sexual arousal to work and should only be taken once per day
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Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for ED.

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Sildenafil

From £3.99

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Viagra

From £27.99

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Tadalafil

From £34.99

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Cialis

From £44.99

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Vardenafil

From £27.99

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Cialis Daily

From £89.99

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Spedra

From £22.99

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Levitra

From £32.99

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Viagra Connect

From £21.99

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Cialis Together

From £16.99

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Sildenafil vs Spedra: Key Differences Explained

How Sildenafil and Spedra Work

Both sildenafil (found in Viagra) and Spedra belong to a class of medicines called PDE5 inhibitors. They work by blocking an enzyme that restricts blood flow to the penis, allowing improved circulation when sexually aroused. Neither medication causes automatic erections - sexual stimulation is still required for them to be effective.

Speed of Action: Spedra's Potential Advantage

One key difference lies in how quickly these treatments begin working. Sildenafil typically takes 30-60 minutes to become effective, whilst Spedra may start working within 15-30 minutes for some men. However, individual response times can vary significantly. Food intake, particularly fatty meals, can delay both medications' onset of action.

Duration and Effectiveness Comparison

Both treatments offer similar duration of action, with effects lasting approximately 4-6 hours. Clinical studies suggest both medications have comparable effectiveness rates for treating erectile dysfunction, with success rates typically ranging from 60-80% depending on the underlying cause and individual factors.

Side Effect Profiles

Common side effects for both medications include headache, facial flushing, nasal congestion, and indigestion. Spedra may have a slightly lower incidence of visual disturbances compared to sildenafil, though this side effect is relatively uncommon with both treatments. Most side effects are mild and temporary.

Dosage Options and Flexibility

Sildenafil is available in 25mg, 50mg, and 100mg strengths, with 50mg being the typical starting dose. Spedra comes in 50mg, 100mg, and 200mg tablets. Both allow dose adjustment based on effectiveness and tolerability, always under medical supervision.

Cost Considerations: Generic Sildenafil Advantage

Generic sildenafil offers substantial cost savings compared to both branded Viagra and Spedra. The active ingredient and effectiveness remain identical to the branded version, making it an economical choice for long-term treatment. At EverydayMeds, patients can choose between branded Viagra or generic sildenafil at checkout, allowing flexibility based on personal preference and budget.

Safety and Contraindications

Both medications share similar contraindications, including use with nitrate medications, severe cardiovascular disease, and recent heart attack or stroke. Neither should be combined with other ED treatments. A thorough medical assessment is essential before starting either treatment.

Making Your Choice

The decision between sildenafil and Spedra often depends on individual factors such as response time preferences, cost considerations, and tolerability. Many men find generic sildenafil provides excellent results at a fraction of the cost of newer alternatives. Clinical consultation helps determine the most suitable option based on your medical history and treatment goals.

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