Orlistat vs Xenical: Your Complete Buying Guide
Orlistat vs Xenical: What's the Difference?
When choosing the best orlistat brand, you're comparing two clinically identical medicines. Generic Orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at the same dose. Both work by blocking approximately one third of dietary fat absorption in the gut, supporting weight management when used alongside a reduced-calorie, lower-fat diet.
The primary difference lies in cost. At EverydayMeds, generic Orlistat 120mg costs £29.69 for a 4-week supply (84 capsules) with code EDM10, while Xenical costs £38.69 for the same period - saving you £9 per month by choosing generic.
Price Comparison: Orlistat vs Xenical
Here's how the costs compare across different treatment periods with our 10% EDM10 discount:
Orlistat 120mg (Generic):
• 2 weeks (42 capsules): £15.20 with EDM10
• 4 weeks (84 capsules): £29.69 with EDM10
• 8 weeks (168 capsules): £57.59 with EDM10
• 12 weeks (252 capsules): £86.39 with EDM10
Xenical 120mg (Branded):
• 2 weeks (42 capsules): £19.35 with EDM10
• 4 weeks (84 capsules): £38.69 with EDM10
• 8 weeks (168 capsules): £78.29 with EDM10
• 12 weeks (252 capsules): £116.09 with EDM10
Over a 12-week treatment period, choosing generic Orlistat saves £29.70 compared to Xenical while delivering identical clinical benefits.
Consider Alli 60mg as an Alternative
For those preferring a lower-strength option, Alli 60mg contains half the dose of prescription-strength orlistat. While clinically less potent, it may suit patients wanting a gentler introduction to orlistat treatment. Alli costs £26.09 for a 4-week supply with EDM10, though you'll need 6 capsules daily versus 3 with prescription-strength options.
Which Should You Choose?
Most patients choose generic Orlistat 120mg for the cost savings without compromising effectiveness. However, some prefer branded Xenical. Both require the same online clinical assessment by our UK-licensed prescribers and are dispensed from our GPhC-registered Leicester pharmacy.
Your choice may depend on personal preference and budget. Both medicines work identically, blocking approximately one third of dietary fat when taken with meals containing fat. Side effects, dosing (one capsule three times daily with meals), and clinical monitoring requirements are identical.
How to Order Your Chosen Treatment
Whether you choose Orlistat or Xenical, our ordering process is straightforward. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber will review your information and, if clinically appropriate, issue a prescription.
Both treatments are prescription-only medicines requiring individual clinical assessment. Our prescribers evaluate your BMI, medical history, and suitability for orlistat treatment before approving any prescription.
Next Day Delivery Across the UK
Once prescribed, we'll dispatch your chosen treatment for next day delivery in discreet packaging. The prescription cost is included in our prices - no separate GP appointment needed. Use code EDM10 for 10% off every order, whether you're a new or returning customer.


