Understanding Aciclovir Tablet Strengths and Dosing
Standard Aciclovir Dosage for Cold Sores
The typical adult dose for treating cold sores is 400mg taken five times daily for five days, starting as soon as symptoms appear. Some patients may be prescribed 200mg five times daily, though 400mg is more commonly recommended for optimal effectiveness. Treatment should ideally begin during the tingling phase before blisters fully develop.
Available Aciclovir Strengths
Aciclovir tablets are available in several strengths including 200mg, 400mg, and 400mg formulations. For cold sores specifically, 200mg and 400mg are the most relevant strengths. The 400mg tablets are typically reserved for treating shingles or other more severe herpes infections. EverydayMeds stocks aciclovir 400mg tablets as the primary treatment option for cold sore management.
Topical vs Oral Treatment Options
Alongside oral tablets, aciclovir 5% cream provides localised treatment directly to affected lip areas. Many patients find combining oral aciclovir tablets with topical cream may help address symptoms from multiple angles. The cream should be applied every four hours during waking hours for optimal results.
Alternative Antiviral Medications
Valaciclovir represents an alternative antiviral option, often prescribed as 500mg tablets taken twice daily for three days. Some patients may find this dosing schedule more convenient than the five-times-daily aciclovir regimen. Both medications work similarly to reduce cold sore duration and severity when taken promptly.
Dosage Considerations and Timing
Starting treatment within 24 hours of symptom onset provides the best chance of reducing outbreak severity. The five-day course should be completed even if symptoms improve earlier. Patients with frequent outbreaks may be considered for suppressive therapy using different dosing schedules, though this requires medical assessment and ongoing monitoring.






