Aciclovir Dosage Strengths for Cold Sores Treatment

Aciclovir is available in multiple dosage strengths for treating cold sores on lips, with 400mg tablets being the most commonly prescribed strength for adults. The correct dosage depends on whether you're treating an active outbreak or taking preventative therapy. EverydayMeds offers prescription aciclovir in various strengths alongside topical treatments to help manage cold sore symptoms effectively when they occur.

  • 400mg tablets - standard adult dose for cold sore outbreaks
  • 200mg tablets - alternative strength for some patients
  • 5% topical cream for localised lip treatment
  • Valaciclovir 500mg as alternative antiviral option
Start your free consultation

Takes less than 2 minutes to complete, 100% online

usp of our everydaymeds for Cold Sore
usp of our everydaymeds for Cold Sore

Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for Cold Sore.

Frame 1321316359 (10).jpg__PID:683ae17e-3507-4d0b-af25-8c85abe00602

Aciclovir Tablets

From £12.99

Learn More
Frame 1321316360 (7).png__PID:dff4fe28-0ac9-428c-81e8-588045465bec

Aciclovir 5% Cream

From £8.99

Learn More
Frame 1321316361 (9).png__PID:a273f1c4-f302-426c-a281-03d0042e6c32

Valaciclovir

From £18.99

Learn More
Frame 1321316362 (7).png__PID:6fbcd9fa-032a-4beb-9e7c-b485a775f164

Valtrex

From £34.99

Learn More

Understanding Aciclovir Tablet Strengths and Dosing

Standard Aciclovir Dosage for Cold Sores

The typical adult dose for treating cold sores is 400mg taken five times daily for five days, starting as soon as symptoms appear. Some patients may be prescribed 200mg five times daily, though 400mg is more commonly recommended for optimal effectiveness. Treatment should ideally begin during the tingling phase before blisters fully develop.

Available Aciclovir Strengths

Aciclovir tablets are available in several strengths including 200mg, 400mg, and 400mg formulations. For cold sores specifically, 200mg and 400mg are the most relevant strengths. The 400mg tablets are typically reserved for treating shingles or other more severe herpes infections. EverydayMeds stocks aciclovir 400mg tablets as the primary treatment option for cold sore management.

Topical vs Oral Treatment Options

Alongside oral tablets, aciclovir 5% cream provides localised treatment directly to affected lip areas. Many patients find combining oral aciclovir tablets with topical cream may help address symptoms from multiple angles. The cream should be applied every four hours during waking hours for optimal results.

Alternative Antiviral Medications

Valaciclovir represents an alternative antiviral option, often prescribed as 500mg tablets taken twice daily for three days. Some patients may find this dosing schedule more convenient than the five-times-daily aciclovir regimen. Both medications work similarly to reduce cold sore duration and severity when taken promptly.

Dosage Considerations and Timing

Starting treatment within 24 hours of symptom onset provides the best chance of reducing outbreak severity. The five-day course should be completed even if symptoms improve earlier. Patients with frequent outbreaks may be considered for suppressive therapy using different dosing schedules, though this requires medical assessment and ongoing monitoring.

How it
Works?

Group 469326.png__PID:d1d71928-56cc-4f79-bdc7-0a45d0bc6b99
Background (1).png__PID:62282697-4455-4e74-a869-705c14f98b30
Background (3).png__PID:72aeaaf6-bb5b-4dd5-8914-6efdf80a1555

Start your assessment
for Cold Sore

Start your journey to better health today.

List.svg__PID:b4a5b990-cf62-48e4-ba8f-0a8bffce6cc6

Start your journey to better health today.

Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

Start My Assessment

Returning customer?

Log in to Your Account

FAQs

Frequently asked questions

Still have questions?

Our UK pharmacists are happy to help. There is no charge and no obligation.

  • Mon–Fri, 9am–5pm
What strength of aciclovir is best for cold sores?
400mg tablets taken five times daily for five days is the standard adult dose for cold sores. Some patients may be prescribed 200mg five times daily depending on individual circumstances.
How quickly should I start aciclovir treatment?
Begin treatment as soon as you feel the first tingling or burning sensation, ideally within 24 hours. Starting early provides the best chance of reducing outbreak severity and duration.
Can I use aciclovir cream alongside tablets?
Many patients use both oral aciclovir tablets and 5% topical cream together for comprehensive treatment. The combination may help address cold sore symptoms from different approaches when used as directed.
Is valaciclovir better than aciclovir for cold sores?
Both medications are effective antivirals for cold sores. Valaciclovir 500mg twice daily may offer more convenient dosing compared to aciclovir's five-times-daily schedule, though both work similarly when taken properly.
How long should I take aciclovir tablets for?
The standard course is five days of treatment, even if symptoms improve earlier. Complete the full prescribed course to ensure optimal effectiveness against the viral infection.