Omeprazole Side Effects vs Lansoprazole Comparison

When choosing between omeprazole and lansoprazole for acid reflux treatment, understanding their side effect profiles is crucial. Both are proton pump inhibitors (PPIs) that effectively reduce stomach acid production, but they may affect individuals differently. This comprehensive comparison examines the side effects of omeprazole versus lansoprazole to help you make an informed decision about your acid reflux treatment.

  • Common omeprazole side effects include headache, nausea, and stomach pain
  • Lansoprazole may cause diarrhoea, dizziness, and dry mouth more frequently
  • Both medications can affect nutrient absorption with long-term use
  • Individual tolerance varies between these PPI medications
Start your free consultation

Takes less than 2 minutes to complete, 100% online

usp of our everydaymeds for Acid Reflux
usp of our everydaymeds for Acid Reflux

Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for Acid Reflux & Heartburn Treatment.

Frame 1321316359 (4).jpg__PID:471262e0-b5c1-4a81-8645-798924de6af3

Omeprazole 20mg

From £12.99

Learn More
Frame 1321316360 (4).png__PID:edbd79c0-7975-453d-b880-d8404a209232

Lansoprazole 15mg Capsules

From £5.99

Learn More
Frame 1321316361 (6).png__PID:dc692acd-7ef0-4d11-94cc-c9625acc0a5d

Famotidine Tablets

From £8.49

Learn More
Frame 1321316362 (3).png__PID:c3206fc2-75dd-4646-97ef-62f7d86d8e74

Lansoprazole 15mg Orodispersible Tablets

From £8.49

Learn More
Frame 1321316363 (3).png__PID:87837d9a-6a6c-4bd3-8dc1-00bdbeb52460

Losec MUPS 20mg Tablets

From £29.99

Learn More
Frame 1321316387 (1).png__PID:8814b58d-07c6-4357-8cab-3bf394b7bd4d

Pantoprazole

From £5.99

Learn More
Frame 1321316388 (1).png__PID:7ee9715c-b838-4f97-aae7-92a4bf86c0f8

Rabeprazole

From £19.99

Learn More
Frame 1321316389 (1).png__PID:a28e97f3-0d1c-4846-9dd7-ad8e0eddbe71

Esomeprazole

From £16.99

Learn More

Understanding Side Effects: Omeprazole vs Lansoprazole

Common Side Effects of Omeprazole

Omeprazole, available as 20mg capsules through EverydayMeds, is generally well-tolerated but may cause several side effects. The most frequently reported include headache (affecting up to 7% of users), stomach pain, nausea, and diarrhoea. Some patients experience dizziness, flatulence, or constipation. Less common but notable side effects include dry mouth, drowsiness, and skin reactions such as rash or itching.

Lansoprazole Side Effect Profile

Lansoprazole 15mg capsules, also available through EverydayMeds, shares many side effects with omeprazole but with different frequencies. Diarrhoea appears more common with lansoprazole, whilst headache may be less frequent. Patients often report dry mouth, abdominal pain, and dizziness. Some individuals experience fatigue, skin rash, or changes in liver enzyme levels during treatment.

Serious Side Effects Comparison

Both medications carry similar risks for serious side effects, though these remain uncommon. Long-term use of either omeprazole or lansoprazole may increase risk of bone fractures, particularly in elderly patients or those taking high doses. Vitamin B12 deficiency can develop with prolonged treatment, as both PPIs reduce stomach acid needed for B12 absorption. Magnesium deficiency is another potential concern with extended use.

Drug Interactions and Considerations

Omeprazole tends to have more significant drug interactions than lansoprazole. It can affect warfarin metabolism, potentially increasing bleeding risk, and may reduce effectiveness of clopidogrel. Lansoprazole generally has fewer clinically significant interactions, making it potentially preferable for patients taking multiple medications. Both can affect absorption of certain drugs requiring acidic conditions.

Choosing Between Treatment Options

When comparing omeprazole and lansoprazole, individual tolerance often determines the best choice. If you experience persistent headaches with omeprazole, lansoprazole might be more suitable. Conversely, if lansoprazole causes troublesome diarrhoea, omeprazole could be preferable. EverydayMeds offers both options alongside alternatives like pantoprazole 20mg tablets and famotidine tablets, providing flexibility to find your optimal treatment. Branded Losec MUPS 20mg tablets offer another omeprazole option for those preferring branded medications.

Alternative PPI Options

Beyond omeprazole and lansoprazole, EverydayMeds provides additional acid reflux treatments including esomeprazole tablets and pantoprazole tablets. These alternatives may suit patients who experience side effects with first-line PPIs. Famotidine tablets, an H2 receptor antagonist, offers a different mechanism of action for those preferring non-PPI treatment or experiencing PPI-related side effects.

How it
Works?

Group 469326.png__PID:d1d71928-56cc-4f79-bdc7-0a45d0bc6b99
Background (1).png__PID:62282697-4455-4e74-a869-705c14f98b30
Background (3).png__PID:72aeaaf6-bb5b-4dd5-8914-6efdf80a1555

Start your assessment for Acid Reflux & Heartburn

Start your journey to better health today.

List.svg__PID:b4a5b990-cf62-48e4-ba8f-0a8bffce6cc6

Start your journey to better health today.

Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

Start My Assessment

Returning customer?

Log in to Your Account

Frequently Asked Question