Get Back on Track with Prescription Weight Loss
Why Some People Gain Weight on Orlistat
If you're experiencing weight gain whilst taking orlistat, several factors may be involved. Orlistat works by blocking approximately one third of dietary fat absorption when taken alongside a reduced-calorie, lower-fat diet. However, weight management depends on overall calorie balance, not just fat intake. Some people may compensate by eating more carbohydrates or larger portions, which can impact results. Additionally, the 60mg strength in some preparations provides half the potency of prescription-strength 120mg orlistat.
Prescription-Strength Orlistat 120mg - £16.89
Our GPhC-registered pharmacy supplies prescription orlistat 120mg following clinical assessment by UK-licensed prescribers. At £16.89 for a 2-week supply (or £15.20 with EDM10), this represents the most cost-effective option for accessing full-strength orlistat. The 120mg dose provides maximum clinical effect, blocking approximately one third of dietary fat when taken three times daily with main meals. Longer courses offer better value: 12-week supplies from £95.99 (£86.39 with EDM10).
Xenical 120mg - Branded Alternative
Xenical contains the same 120mg orlistat dose as generic versions but comes from original manufacturer Roche. Some patients prefer the branded option for consistency. Xenical 120mg starts from £21.50 for 42 capsules, with 12-week supplies at £128.99 (£116.09 with code EDM10). Both generic orlistat and Xenical require prescription following individual clinical assessment and work identically to support weight management.
Alli 60mg - Lower Strength Option
Alli provides 60mg orlistat - half the prescription strength. This lower dose may be suitable for those preferring a gentler approach or experiencing side effects with 120mg preparations. Alli 60mg costs £28.99 for a 4-week supply (£26.09 with EDM10). While lower strength means reduced potency, Alli still works by the same mechanism of blocking dietary fat absorption when combined with appropriate dietary changes.
Online Prescription Process
Access prescription orlistat through our regulated online service. Complete a clinical questionnaire covering medical history, current medications, and weight management goals. UK-licensed prescribers review each application individually, issuing prescriptions where clinically appropriate. Our Leicester-based pharmacy then dispenses and dispatches your medication with discreet next day delivery. No separate GP appointment needed - prescription costs included in our transparent pricing.
Maximising Orlistat Effectiveness
To optimise results, maintain a reduced-calorie diet with no more than 30% calories from fat (approximately 15g fat per meal). This approach minimises gastrointestinal side effects while supporting weight management. Consider a daily multivitamin taken at bedtime to replace fat-soluble vitamins. Regular physical activity enhances results when combined with orlistat therapy. Always follow prescriber guidance and report concerns about weight gain or treatment effectiveness.


