Alli vs Orlistat vs Xenical: Which to Buy in 2024?

pricing for mounjaro and wegovy weight loss

Wondering whether Alli, Orlistat, or Xenical works best for weight loss? All three contain the active ingredient orlistat, which blocks approximately one third of dietary fat absorption. The key differences are strength and price: Orlistat 120mg (generic) from £15.20, Xenical 120mg (branded) from £19.35, and Alli 60mg (lower strength) from £26.09. All available through our GPhC-registered pharmacy with 10% off using code EDM10. Get your prescription online following clinical assessment by UK-licensed prescribers, with next-day delivery across the UK.

  • Same active ingredient - orlistat blocks approximately one third of dietary fat
  • Orlistat 120mg costs £9 less per month than branded Xenical
  • Online prescription service - no GP appointment needed
  • Next-day delivery from GPhC-registered Leicester pharmacy
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Orlistat vs Xenical vs Alli: Price & Strength Guide

Does Alli Work for Weight Loss? Comparing Your Options

Alli, Orlistat, and Xenical all contain the same fat-blocking ingredient - orlistat. The question isn't whether Alli works, but which strength and brand offers the best value for your weight management goals. Orlistat works by inhibiting lipase enzymes in your gut, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, supporting weight loss when combined with a reduced-calorie, lower-fat diet.

Orlistat 120mg vs Xenical 120mg: Identical Effect, Different Price

Both Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at the same dose. The clinical effect is identical - both block the same amount of dietary fat absorption. The only meaningful difference is cost. Generic Orlistat 120mg costs £29.69 for a 4-week supply (with EDM10), whilst branded Xenical costs £38.69 - a saving of £9 per month by choosing the generic option. Both require a prescription following clinical assessment by a UK-licensed prescriber.

Alli 60mg: The Lower-Strength Alternative

Alli contains half the dose of prescription-strength orlistat at 60mg per capsule. Whilst clinically less potent than the 120mg versions, Alli may be suitable for those preferring a lower-strength starting point. At £26.09 for a 4-week supply (with EDM10), Alli offers a middle-ground option between no treatment and full prescription strength. However, the reduced dose means it blocks a smaller proportion of dietary fat compared to 120mg formulations.

Which Should You Buy? Our Recommendation

For maximum clinical effect and best value, generic Orlistat 120mg offers the optimal combination. You'll get the full prescription strength at the lowest cost - £57.59 for an 8-week supply with code EDM10, compared to £78.29 for equivalent Xenical. However, some patients prefer branded Xenical, and that's a valid choice. If you're concerned about starting at full strength, Alli 60mg provides a gentler introduction to orlistat treatment.

How to Order Online Through EverydayMeds

Our online prescription service eliminates the need for a GP appointment. Complete our clinical assessment questionnaire, which covers your medical history, current medications, and BMI details. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Your chosen treatment is then dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next-day delivery available.

Pricing Comparison: All Options

Orlistat 120mg: 2 weeks £15.20, 4 weeks £29.69, 8 weeks £57.59, 12 weeks £86.39 (with EDM10). Xenical 120mg: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 (with EDM10). Alli 60mg: 4 weeks £26.09, 8 weeks £49.49, 12 weeks £116.99 (with EDM10). Use code EDM10 for 10% off every order, available to new and returning customers.

Important Safety Information

All orlistat products may cause gastrointestinal side effects, particularly when eating high-fat meals. Keep your fat intake to approximately 15g per meal to minimise side effects. Most patients experience fewer side effects as they adapt to a lower-fat diet. Orlistat is prescription-only at 120mg strength and requires clinical assessment to determine suitability. Always follow guidance from your prescriber and seek medical advice if you experience severe or persistent side effects.

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