Generic vs Branded: Making Your Purchase Decision
Orlistat vs Xenical: The Key Differences
When comparing Orlistat 120mg and Xenical 120mg, the most important fact is that both contain exactly the same active ingredient at identical doses. Orlistat is the generic version, while Xenical is the branded version manufactured by Roche. Clinically, they work in exactly the same way - both block approximately one third of dietary fat absorption to support weight management alongside a reduced-calorie, lower-fat diet.
The primary difference is cost. At EverydayMeds, Orlistat 120mg costs £32.99 for a 4-week supply (£29.69 with EDM10), while Xenical 120mg costs £42.99 (£38.69 with EDM10). Over a typical 12-week course, choosing generic Orlistat could save you over £30 compared to branded Xenical.
Which Should You Buy?
For most patients, generic Orlistat 120mg offers the best value without compromising on clinical effectiveness. Both products require the same online clinical assessment by our UK-licensed prescribers and work identically in your body. Some patients prefer the branded option, but there's no clinical advantage - the choice comes down to personal preference and budget.
If you're looking for a lower-strength option to start with, Alli 60mg contains half the dose and is available from £26.09 for a 4-week supply with EDM10. While less potent than the 120mg prescription versions, it may suit those preferring a gentler introduction to orlistat treatment.
How Both Products Work
Whether you choose Orlistat or Xenical, the mechanism is identical. Both work by inhibiting lipase enzymes in your gut, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your system. Neither product acts on your brain or suppresses appetite - they work locally in your digestive system to reduce calorie intake from dietary fat.
Our Pricing and Packages
EverydayMeds offers both options with competitive pricing and flexible pack sizes. For Orlistat 120mg: 2 weeks (42 capsules) from £15.20, 4 weeks (84 capsules) from £29.69, 8 weeks (168 capsules) from £57.59, and 12 weeks (252 capsules) from £86.39 - all with EDM10 discount. Xenical 120mg is available in the same pack sizes, starting from £19.35 for 2 weeks with code EDM10.
Getting Started Today
Both Orlistat and Xenical require a prescription following clinical assessment. Our streamlined online process means you can complete your consultation, receive prescriber review, and have your chosen treatment dispensed by our GPhC-registered pharmacy - all without visiting a GP. Next day delivery is available across the UK with discreet, tracked packaging. Start your online consultation now to determine which option suits your needs and budget best.


