Orlistat vs Xenical: When Best to Take & Which to Buy

pricing for mounjaro and wegovy weight loss

Choosing between generic orlistat 120mg and branded Xenical 120mg? Both contain identical active ingredients and work exactly the same way — the key difference is price. Generic orlistat starts from £29.69 for 4 weeks (with EDM10), while Xenical costs £38.69 for the same supply. Both block approximately one third of dietary fat when taken with meals. Our UK-licensed prescribers can assess your suitability and help you choose the most cost-effective option. Complete your online consultation today and save 10% with code EDM10 on your first order.

  • Identical clinical effect — orlistat and Xenical contain the same 120mg active ingredient
  • Significant savings — generic orlistat costs £9 less per month than branded Xenical
  • Same dosing schedule — one capsule with each main meal containing fat, up to 3 times daily
  • UK prescription included — no separate GP appointment needed with our online service
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Orlistat vs Xenical: Making Your Purchase Decision

Same Active Ingredient, Different Prices

When deciding between orlistat 120mg and Xenical 120mg, the most important fact is that both contain exactly the same active ingredient at identical doses. Generic orlistat and branded Xenical work in precisely the same way — blocking approximately one third of dietary fat absorption when taken with meals. The clinical effect is equivalent, making your choice primarily about cost and personal preference.

Price Comparison: Orlistat vs Xenical

Generic orlistat offers substantial savings compared to branded Xenical. For a 4-week supply (84 capsules), orlistat costs £32.99 (£29.69 with EDM10) while Xenical costs £42.99 (£38.69 with EDM10). Over 12 weeks, you'll save over £30 by choosing generic orlistat at £86.39 compared to Xenical at £116.09. Both options include your prescription following online clinical assessment by our UK-licensed prescribers.

When to Take Orlistat or Xenical

Both orlistat and Xenical follow the same dosing schedule for optimal effectiveness. Take one 120mg capsule with each main meal containing fat, up to three times daily. The best time is immediately before, during, or up to one hour after eating. If you skip a meal or eat a fat-free meal, you can omit that dose. This consistent timing helps maximise fat blocking while minimising gastrointestinal side effects.

Alli 60mg: Lower-Strength Alternative

For those preferring a gentler starting point, Alli 60mg offers half the strength of prescription orlistat. At £26.09 for 4 weeks (with EDM10), Alli provides a lower-dose option with typically milder side effects. However, the fat-blocking effect is also reduced compared to the 120mg prescription versions.

Which Should You Buy?

Choose generic orlistat 120mg if you want maximum value — you'll get the same clinical benefit as Xenical while saving money. Choose Xenical 120mg if you prefer the branded option and don't mind paying extra. Both require online clinical assessment and are dispensed by our GPhC-registered pharmacy. Complete your consultation today and start your weight management journey with next-day delivery across the UK.

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