Compare Prices: Generic vs Branded Weight Loss Treatment
Orlistat vs Xenical: Identical Clinical Effect
Orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through your body. Clinically, they're equivalent - the key difference is cost savings with generic orlistat.
Cost Comparison: Significant Monthly Savings
Generic orlistat offers substantial savings over branded Xenical. For a 4-week supply, orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you save £33+ choosing generic orlistat at £95.99 versus Xenical's £128.99. Both require prescription following clinical assessment.
Alli 60mg: Lower Strength Alternative
Alli contains half the orlistat dose at 60mg per capsule. This lower strength may suit those preferring a gentler starting point, though it blocks less dietary fat than prescription-strength options. Alli 4-week supply costs £28.99 (£26.09 with EDM10).
How Prescription Orlistat Works
Orlistat acts locally in your digestive system, not your brain. It inhibits pancreatic lipase enzymes responsible for breaking down dietary fats. When these enzymes are blocked, approximately one third of fat from meals cannot be digested or absorbed. This reduces calorie intake from dietary fat when combined with a reduced-calorie, lower-fat diet and increased physical activity.
Who May Be Suitable for Treatment
Prescription orlistat may be suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions like diabetes or high blood pressure. Our UK-licensed prescribers assess eligibility through online clinical consultation. Treatment works best alongside structured dietary changes limiting fat to approximately 15g per meal.
Online Prescription Process
Complete our confidential health questionnaire covering medical history, current medications, and BMI information. A qualified UK prescriber reviews your assessment and issues prescription where clinically appropriate. Your medication is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly with next day tracked delivery across the UK.
Managing Treatment Expectations
Orlistat may help support weight management when used correctly alongside reduced-calorie, lower-fat diet and regular exercise. Individual results vary significantly. Most side effects are gastrointestinal and linked to dietary fat intake - keeping meals low in fat minimises these effects. Always follow your prescriber's guidance throughout treatment.


