Orlistat vs Xenical: Which Should You Choose Long Term?
Long-Term Orlistat Use: What You Need to Know
Can you take orlistat long term? Yes, both Orlistat 120mg and Xenical 120mg can be used for extended periods when prescribed and monitored by UK healthcare professionals. Long-term treatment may be appropriate for sustained weight management alongside a reduced-calorie, lower-fat diet and regular physical activity. Your prescriber will assess whether continued treatment remains suitable for your individual circumstances.
Orlistat 120mg vs Xenical 120mg: The Facts
Both products contain identical amounts of the same active ingredient - orlistat 120mg. They work by blocking approximately one third of dietary fat from being absorbed in your gut. The clinical effect is identical whether you choose generic Orlistat or branded Xenical. The key difference is cost: Orlistat 4-week supply costs £29.69 versus Xenical at £38.69 with EDM10 discount - saving you over £100 annually on long-term treatment.
Cost Comparison for Long-Term Treatment
For 12-week supplies with EDM10 discount: Generic Orlistat costs £86.39 versus Xenical at £116.09 - a £29.70 saving every three months. Over a year, choosing Orlistat could save approximately £118 compared to Xenical. Both require the same online clinical assessment and are dispensed by our GPhC-registered pharmacy in Leicester.
Alli 60mg: Lower-Strength Alternative
Alli contains half the dose at 60mg orlistat per capsule. While less potent than prescription-strength options, it may suit those preferring a gentler starting point. Alli 12-week supply costs £116.99 with EDM10. However, prescription-strength Orlistat 120mg offers better value and efficacy for most patients suitable for long-term weight management.
How to Order for Long-Term Use
Complete our online health questionnaire for UK prescriber review. If approved, choose between Orlistat 120mg or Xenical 120mg in 2, 4, 8, or 12-week supplies. Use code EDM10 for 10% off every order. Next-day delivery available across the UK with discreet, tracked packaging from our regulated online pharmacy.


