Which Should You Choose for Long Term Weight Management?
Generic Orlistat vs Branded Xenical: The Clinical Facts
Both generic orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by inhibiting lipase enzymes in your digestive system, blocking approximately one third of dietary fat from being absorbed. Clinically, they are equivalent - the key difference lies in cost and personal preference.
Cost Comparison for Long Term Use
For sustained weight management, cost becomes significant. Generic orlistat 120mg costs £29.69 for 4 weeks with EDM10, whilst Xenical costs £38.69 for the same period - a saving of £9 monthly. Over 12 weeks, generic orlistat costs £86.39 compared to Xenical's £116.09, saving you nearly £30. Both require prescription following clinical assessment by our UK-licensed prescribers.
Pack Sizes Available
Generic Orlistat 120mg: 2 weeks (42 capsules) £15.20, 4 weeks (84 capsules) £29.69, 8 weeks (168 capsules) £57.59, 12 weeks (252 capsules) £86.39 with EDM10. Xenical 120mg: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 with EDM10. All prices include prescription and clinical assessment.
Alli 60mg: Lower Strength Alternative
Alli contains orlistat at half the prescription strength. At 60mg, it may cause milder gastrointestinal side effects whilst still supporting weight management alongside a reduced-calorie, lower-fat diet. Available in 4-week (42 capsules) £26.09, 8-week (84 capsules) £49.49, and 12-week (252 capsules) £116.99 packs with EDM10.
Long Term Safety Considerations
Whether choosing generic orlistat, Xenical, or Alli, long-term use requires ongoing monitoring. All versions may reduce absorption of fat-soluble vitamins A, D, E, and K. A daily multivitamin taken at bedtime is recommended. Regular review with healthcare professionals ensures continued suitability and effectiveness of treatment.
Managing Side Effects Long Term
Gastrointestinal side effects typically reduce as your diet adapts to lower fat intake. Keeping dietary fat to approximately 15g per meal significantly minimises oily stools, urgency, and flatulence. Most patients find side effects become manageable within the first few weeks of treatment.
How to Order Through EverydayMeds
Complete our online health questionnaire for clinical assessment by a UK-licensed prescriber. If approved, your chosen medication is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address with next-day delivery available. Use code EDM10 for 10% off every order.


