Which Should You Choose: Generic Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When comparing Xenical and Orlistat in the UK, the most important fact is that both contain exactly the same active ingredient - orlistat 120mg. The clinical effect is identical: both block approximately one third of dietary fat absorption when taken with meals. The main difference is price. Generic Orlistat offers significant savings, with a 4-week supply costing £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). That's a potential saving of around £9 per month choosing generic over branded.
Xenical UK Pricing vs Generic Orlistat
Our pricing comparison shows substantial savings with generic Orlistat across all pack sizes. For a 2-week supply: Orlistat costs £16.89 (£15.20 with EDM10) versus Xenical at £21.50 (£19.35 with EDM10). For longer treatment periods, the savings increase - a 12-week supply of Orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10). Both medications work identically, so choosing generic Orlistat can save you over £40 on a 12-week course.
Why Some Patients Choose Xenical
Despite the higher cost, some patients prefer branded Xenical for personal reasons. Xenical is manufactured by Roche and has been available for many years, giving some patients confidence in the established brand. However, generic orlistat undergoes the same rigorous testing and regulatory approval. Both are dispensed by GPhC-registered pharmacies and meet identical quality standards. The choice often comes down to personal preference and budget considerations.
Alli 60mg: The Lower-Strength Alternative
For those considering a lower-strength option, Alli 60mg contains half the dose of prescription orlistat. A 4-week supply costs £28.99 (£26.09 with EDM10). While less potent than the 120mg prescription versions, Alli may be suitable for some patients who prefer starting with a lower dose. All three options - Orlistat 120mg, Xenical 120mg, and Alli 60mg - work by the same mechanism of blocking dietary fat absorption.
How to Order Online
Ordering either Orlistat or Xenical through our online service is straightforward. Complete our clinical questionnaire which covers your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and, if clinically appropriate, issues a prescription. Your chosen medication is then dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available. Use code EDM10 at checkout for 10% off every order.
Clinical Assessment and Safety
Both Orlistat and Xenical require prescription following clinical assessment. Our prescribers ensure the medication is suitable for your individual circumstances, considering factors like BMI, medical history, and current medications. Treatment is typically suitable for adults with a BMI of 30 or above, or 28 or above with weight-related health conditions. Both medications must be used alongside a reduced-calorie, lower-fat diet for optimal results and to minimise gastrointestinal side effects.


