Get Your Orlistat Treatment Back on Track
Common Reasons Why Orlistat May Not Be Working
When orlistat doesn't seem to be supporting your weight loss goals, the issue often lies in how it's being used rather than the medication itself. Orlistat works by blocking approximately one third of dietary fat absorption, but this mechanism only functions effectively when meals contain fat and when the medication is taken at the right time. Many patients find their treatment isn't working because they're not taking orlistat with each fat-containing meal, or they're consuming too much fat per meal, leading to uncomfortable side effects that disrupt their routine.
Timing and Diet: The Key to Orlistat Success
Orlistat must be taken immediately before, during, or up to one hour after each main meal containing fat. If you're taking it at random times or forgetting doses with fatty meals, you won't experience its full fat-blocking benefits. Additionally, keeping each meal to approximately 15g of fat helps minimise gastrointestinal side effects while allowing orlistat to work effectively. High-fat meals not only cause unpleasant side effects but can overwhelm the medication's capacity to help manage fat absorption.
Generic Orlistat vs Xenical: Same Effectiveness, Different Prices
Whether you're taking generic orlistat 120mg or branded Xenical 120mg, both contain the same active ingredient at identical doses. If one isn't working, switching between them won't improve effectiveness - the issue is likely with diet or timing rather than the specific product. At EverydayMeds, generic orlistat costs £32.99 for 4 weeks (£29.69 with EDM10), while Xenical costs £42.99 (£38.69 with EDM10). Both require the same approach: three capsules daily with fat-containing meals alongside a reduced-calorie, lower-fat diet.
When to Consider Alli 60mg as an Alternative
Some patients find the 120mg prescription dose too strong initially, leading to side effects that disrupt their treatment routine. Alli 60mg offers half the dose and may be more tolerable while you adjust your diet. Available at £28.99 for 4 weeks (£26.09 with EDM10), Alli can help you establish the right dietary habits before potentially moving to prescription-strength orlistat. However, the lower dose means less fat-blocking effect, so it may provide more gradual results.
Getting Professional Support for Your Treatment
If your orlistat treatment isn't working as expected, our UK-licensed prescribers can review your approach through our online consultation service. They can assess whether your dosing, timing, or diet needs adjustment, or whether orlistat remains the most suitable option for your weight management goals. Our GPhC-registered pharmacy in Leicester can supply 8-week packages (orlistat £63.99, Xenical £86.99, or 12-week supplies for longer-term support, all with 10% off using EDM10.
Order Your Orlistat Treatment Today
Don't let ineffective treatment continue when simple adjustments could make all the difference. Complete our online clinical assessment to get your orlistat prescription reviewed and delivered next-day across the UK. With prices starting from £29.69 for generic orlistat 4-week supply and our 10% discount available on every order, getting back on track with your weight loss support has never been more affordable or convenient.


