Generic Orlistat vs Xenical: The Complete Buying Guide
Orlistat vs Xenical: What's Actually Different?
The most important fact to understand is that generic orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at exactly the same dose. Both work by blocking approximately one third of dietary fat absorption in your gut. The clinical effect is identical - Xenical is simply the branded version manufactured by Roche, whilst generic orlistat offers the same treatment at a lower cost.
Generic orlistat 120mg costs £15.20 for a 2-week supply (42 capsules) with code EDM10, compared to £19.35 for branded Xenical. Over a 12-week course, you could save £29.70 by choosing generic orlistat (£86.39) instead of Xenical (£116.09). Both require the same prescription following clinical assessment.
Why Choose Generic Orlistat 120mg?
Generic orlistat delivers the same clinical benefits as Xenical at a significantly lower price. Our generic orlistat 120mg capsules are sourced through licensed UK pharmaceutical supply chains and dispensed by our GPhC-registered pharmacy. You'll receive exactly the same fat-blocking effect - inhibiting lipase enzymes to prevent absorption of approximately one third of dietary fat from each meal.
Current pricing with EDM10 discount: 4-week supply (84 capsules) £29.69, 8-week supply (168 capsules) £57.59, 12-week supply (252 capsules) £86.39. All prices include your prescription - no separate GP consultation fee required.
When Patients Prefer Xenical
Some patients prefer the reassurance of choosing the original branded version. Xenical 120mg has been available longer and is manufactured by Roche, the company that originally developed orlistat. Whilst more expensive, Xenical offers the identical active ingredient with the same clinical effect as generic versions.
Xenical pricing with EDM10: 4-week supply £38.69, 8-week supply £78.29, 12-week supply £116.09. Like generic orlistat, Xenical requires prescription following online clinical assessment by our UK-licensed prescribers.
Consider Alli 60mg as an Alternative
Alli contains half the strength of prescription orlistat at 60mg per capsule. It works through the same mechanism - blocking approximately one third of dietary fat absorption - but at a lower dose. This may result in milder gastrointestinal side effects, though the fat-blocking effect is correspondingly reduced.
Alli 60mg pricing with EDM10: 4-week supply £26.09, 8-week supply £49.49, 12-week supply £116.99. Alli represents a middle option between prescription-strength orlistat and no treatment.
How to Order - Same Process for Both
Whether you choose generic orlistat or branded Xenical, the ordering process is identical. Complete our online health questionnaire covering your medical history, current medications, and BMI. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. We then dispense your chosen treatment and dispatch for next day delivery in discreet packaging.
All treatments work best alongside a reduced-calorie, lower-fat diet with no more than 15g fat per meal. Higher fat meals increase the likelihood of gastrointestinal side effects including oily stools and urgent bowel movements. Use code EDM10 for 10% off every order.


