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Prescription Orlistat for Weight Loss UK
Orlistat is a prescription-only weight loss medicine that may help support weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity. Available as generic orlistat 120mg capsules, branded Xenical 120mg, or lower-strength Alli 60mg, orlistat works by blocking approximately one third of dietary fat from being absorbed in your digestive system.
How Orlistat Supports Weight Management
Orlistat works locally in your gut by inhibiting lipase enzymes responsible for breaking down dietary fat. When these enzymes are blocked, approximately one third of the fat you eat cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your digestive system, potentially reducing calorie intake from dietary fat as part of your weight management plan.
Orlistat Pricing and Pack Sizes
Our prescription orlistat 120mg starts from just £15.20 for a 2-week supply (42 capsules) with code EDM10. For longer treatment, choose our 12-week supply (252 capsules) at £86.39 with EDM10 - saving over £9 compared to the regular price. Branded Xenical 120mg is available from £19.35 for 2 weeks, while Alli 60mg starts from £26.09 for a 4-week supply. All prices include 10% off with code EDM10.
Online Prescription Process
Getting your prescription weight loss treatment is straightforward. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber will review your information and, if clinically appropriate, issue your prescription. Your medication is then dispensed by our GPhC-registered pharmacy in Leicester and dispatched for next day delivery across the UK.
Who May Be Suitable for Orlistat
Orlistat may be suitable for adults with a BMI of 30 kg/m² or above, or those with a BMI of 28 kg/m² or above with weight-related health conditions such as type 2 diabetes, high blood pressure, or high cholesterol. Suitability is assessed individually through clinical consultation, and treatment must always be combined with dietary and lifestyle changes for optimal results.
Managing Side Effects
Like all prescription medicines, orlistat may cause side effects, most commonly gastrointestinal effects related to unabsorbed fat. These can be minimised by keeping dietary fat intake low - approximately 15g fat per meal. Most side effects reduce over time as your diet adapts. If side effects are severe or persistent, consult your healthcare professional for guidance.


