Understanding Orlistat Side Effects and Your Options
Does Orlistat Cause Increased Thirst?
Increased thirst is not among the commonly reported side effects of orlistat. The most frequent side effects are gastrointestinal, including oily stools, increased bowel movements, and abdominal discomfort. These occur because orlistat blocks approximately one third of dietary fat absorption, with unabsorbed fat passing through your digestive system. If you experience unusual thirst whilst taking orlistat, consult your prescriber to rule out other causes such as dehydration or underlying health conditions.
How Orlistat Works for Weight Management
Orlistat 120mg works by inhibiting lipase enzymes in your gut, preventing the absorption of approximately one third of dietary fat from meals. This can support weight management when combined with a reduced-calorie, lower-fat diet and increased physical activity. At EverydayMeds, we stock orlistat 120mg from £16.89 for 42 capsules (2 weeks), or £15.20 with code EDM10. Our 12-week supply costs £95.99, reduced to £86.39 with your discount code.
Orlistat vs Xenical vs Alli - Which Should You Choose?
All three contain the same active ingredient - orlistat - but at different strengths. Orlistat 120mg and Xenical 120mg are prescription-only and clinically equivalent, with generic orlistat offering better value at £29.69 for 4 weeks (with EDM10) compared to Xenical at £38.69. Alli 60mg is half-strength and may be suitable for those preferring a lower-dose option at £26.09 for 4 weeks with EDM10. Your prescriber will recommend the most appropriate option following clinical assessment.
Managing Side Effects Whilst Taking Orlistat
Gastrointestinal side effects can be minimised by keeping meals low in fat - approximately 15g fat per meal. Most side effects reduce over time as your diet adapts. Take a multivitamin supplement at bedtime (at least 2 hours after your last orlistat dose) as the medication may reduce absorption of fat-soluble vitamins A, D, E and K. If side effects persist or worsen, contact your healthcare professional for advice.
Getting Your Prescription Weight Loss Treatment
Our streamlined process makes accessing prescription weight loss medication simple. Complete our online health questionnaire, which is reviewed by a UK-licensed prescriber who will assess your suitability for treatment. If approved, your medication is dispensed by our GPhC-registered pharmacy and delivered discreetly to your address with next day delivery. The prescription is included in the price - no separate GP appointment required.


