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Orlistat Prescription Weight Loss Options UK
Orlistat is a prescription-only weight loss medication that works by blocking approximately one third of the fat you eat from being absorbed. Available as generic orlistat 120mg, branded Xenical 120mg, or lower-strength Alli 60mg, these treatments may help support weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Our GPhC-registered pharmacy in Leicester provides orlistat prescriptions following an online clinical assessment by UK-licensed prescribers. Generic orlistat 120mg starts from £16.89 for 2 weeks (£15.20 with EDM10), while branded Xenical costs £21.50 for 2 weeks (£19.35 with EDM10). All orders qualify for 10% off with code EDM10.
How Orlistat Works for Weight Management
Orlistat acts locally in your digestive system by inhibiting lipase enzymes responsible for breaking down dietary fat. When these enzymes are blocked, approximately one third of consumed fat cannot be absorbed and passes naturally through your body. This mechanism may help reduce calorie intake from dietary fat as part of a structured weight management programme.
The medication works best when combined with meals containing no more than 15g of fat per serving. Higher fat intake increases the likelihood of gastrointestinal side effects, which are the body's natural response to unabsorbed fat. Taking one capsule with each main meal (maximum 3 per day) provides optimal support for your weight loss goals.
Prescription Options and Pricing
Choose from three clinically proven options. Generic orlistat 120mg offers the most cost-effective treatment at £32.99 for 4 weeks (£29.69 with EDM10). Branded Xenical 120mg contains the identical active ingredient at £42.99 for 4 weeks (£38.69 with EDM10). Both require a prescription following clinical assessment.
Alli 60mg provides a lower-strength alternative at £28.99 for 4 weeks (£26.09 with EDM10). All treatments block dietary fat absorption through the same mechanism, with the 120mg options offering greater clinical potency. Longer treatment courses provide better value - 12-week supplies cost £95.99 for generic orlistat (£86.39 with EDM10).
Online Prescription Process
Complete your online health questionnaire covering medical history, current medications, and BMI information. A UK-licensed prescriber reviews your assessment to determine treatment suitability. Orlistat may be appropriate for adults with a BMI of 30 or above, or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure.
Once approved, your prescription is dispensed by our GPhC-registered pharmacy and dispatched for next day delivery. The entire process typically takes 24-48 hours from consultation to delivery, providing faster access than traditional GP appointments while maintaining the same clinical standards.
Safety and Side Effects
Like all prescription medicines, orlistat may cause side effects. Most are gastrointestinal and directly linked to dietary fat intake - including oily stools, increased bowel movements, and abdominal discomfort. These effects can be minimised by keeping meals low in fat and typically reduce as your diet adapts.
Rare but serious side effects require immediate medical attention, including severe abdominal pain or signs of liver problems. A daily multivitamin taken at bedtime is recommended, as orlistat may reduce absorption of fat-soluble vitamins A, D, E, and K.
