How Does Orlistat Work for Weight Loss?

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Orlistat is a prescription weight loss medication that works by blocking approximately one third of dietary fat absorption in your gut. Available as generic orlistat 120mg (from £15.20 with EDM10) or branded Xenical 120mg, it may help support weight management alongside a reduced-calorie, lower-fat diet. Following an online clinical assessment by UK-licensed prescribers, orlistat can be prescribed where appropriate and delivered discreetly from our GPhC-registered pharmacy in Leicester. Complete your consultation today and save 10% with code EDM10 on every order.

  • Blocks approximately one third of dietary fat absorption naturally
  • Prescription strength orlistat from £15.20 per fortnight with EDM10
  • Online consultation with UK-licensed prescribers included
  • Next day delivery from GPhC-registered pharmacy
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Understanding How Orlistat Supports Weight Loss

How Orlistat Works in Your Body

Orlistat works by inhibiting lipase enzymes in your digestive system that break down dietary fat. When these enzymes are blocked, approximately one third of the fat you eat cannot be absorbed and passes naturally through your body. Unlike appetite suppressants that act on the brain, orlistat works locally in your gut and is not significantly absorbed into your bloodstream. This mechanism may help reduce calorie intake from dietary fat when used alongside a reduced-calorie, lower-fat diet and increased physical activity.

Prescription Orlistat Options Available

We offer three clinically proven options: Generic orlistat 120mg provides the most cost-effective treatment from £29.69 for a 4-week supply (84 capsules) with EDM10. Branded Xenical 120mg contains the identical active ingredient at £38.69 for 4 weeks with EDM10. Alli 60mg offers a lower-strength option at £49.49 for 8 weeks (84 capsules) with EDM10. All require clinical assessment, except Alli which is available at the lower strength.

Getting Your Orlistat Prescription Online

Our streamlined process starts with completing a comprehensive online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and, where clinically appropriate, issues your prescription. Your medication is then dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available. The prescription is included in the price, saving you a separate GP appointment.

What to Expect When Taking Orlistat

Orlistat works best when each main meal contains no more than approximately 15g of fat, helping to minimise gastrointestinal side effects. You'll take one capsule with each main meal containing fat, up to three times daily. The unabsorbed fat passes through your system naturally, which can cause oily stools or spotting - this indicates the medication is working. Most patients find side effects reduce over time as they adapt to a lower-fat diet. Start your consultation today to see if orlistat could support your weight management goals.

How it
Works?

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