Which Dosing Schedule Matches Your Weight Goals?
What Are the Doses of Wegovy vs Mounjaro: Key Differences
The doses of Wegovy follow a structured 20-week escalation protocol designed to minimise gastrointestinal side effects whilst maximising efficacy. Wegovy's five-dose journey begins with 0.25mg for weeks 1-4, progressing through 0.5mg (weeks 5-8), 1mg (weeks 9-12), 1.7mg (weeks 13-16), before reaching the 2.4mg maintenance dose from week 17 onwards. This gradual approach allows your body to adapt to semaglutide's GLP-1 receptor activation.
Mounjaro presents a different dosing landscape with six available strengths: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg maximum dose. Unlike Wegovy's fixed escalation, Mounjaro's tirzepatide dosing can be more individualised based on tolerability and response. The dual GLP-1 and GIP receptor mechanism requires careful titration, typically starting at 2.5mg weekly and increasing every four weeks as clinically appropriate.
Wegovy Dosing Schedule and Pricing Structure
Understanding what are the doses of Wegovy means grasping both the clinical rationale and practical costs involved. EverydayMeds offers transparent pricing: 0.25mg starter dose costs £79.99, 0.5mg at £94.99, 1mg at £99.99, 1.7mg at £139.99, and the 2.4mg maintenance dose at £209.99. These prices include the application of discount codes FIRST40 (new customers) or DOSE25 (returning customers) at checkout.
Bundle options provide convenience for patients committed to the complete escalation journey. The Intro Trio bundle (0.25mg, 0.5mg, 1mg) costs £299.99, whilst the Ultimate Stability Trio offers three months of 2.4mg maintenance supply for £649.99. These bundles eliminate the need for multiple orders and ensure consistent supply throughout your weight management programme.
Clinical Evidence Behind Wegovy Dose Selection
The specific doses of Wegovy were established through the comprehensive STEP clinical trial programme. Wilding et al., NEJM, 2021, demonstrated that the 2.4mg maintenance dose achieved approximately 15% average weight loss at 68 weeks when combined with lifestyle interventions. The dose-escalation protocol was specifically designed to optimise both efficacy and tolerability.
STEP 5 trial data confirmed that the 2.4mg maintenance dose sustained approximately clinically studied weight loss at two years, validating the long-term effectiveness of Wegovy's dosing strategy. The recent SELECT cardiovascular outcomes trial further demonstrated a 20% reduction in major cardiovascular events, reinforcing the clinical value of appropriate Wegovy dosing.
How Wegovy's GLP-1 Mechanism Guides Dosing
Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics the natural incretin hormone released after eating. The escalating doses of Wegovy allow gradual adaptation to enhanced satiety signals, reduced gastric emptying, and decreased food cravings. Each dose increase builds upon the previous level's appetite suppression effects whilst minimising the risk of nausea or vomiting that can occur with rapid dose escalation. The 2.4mg maintenance dose represents the optimal balance between maximum therapeutic effect and acceptable tolerability for most patients. This mechanism differs fundamentally from Mounjaro's dual GLP-1/GIP approach, which may require different dosing considerations.
EverydayMeds Ordering Process for Both Medications
Accessing the appropriate doses of Wegovy or Mounjaro through EverydayMeds begins with a comprehensive 3-minute online clinical assessment covering medical history, current medications, and weight management goals. Our GPhC-registered prescribers review each application within 3 working days (24-hour express service available), determining the most suitable starting dose and escalation schedule. Once approved, your prescription-only medicine is dispatched via next-day delivery using temperature-controlled cold-chain logistics. The FlexTouch pen delivery includes clear dosing instructions and injection technique guidance. Our clinical team remains available throughout your treatment journey to support dose adjustments and address any concerns.
Storage Requirements: Wegovy vs Mounjaro Comparison
Both medications require refrigerated storage at 2-8°C before first use, but important differences exist in room temperature stability. Wegovy pens can remain at room temperature (below 30°C) for up to 6 weeks once removed from refrigeration, whilst Mounjaro maintains stability for 21 days at room temperature. This storage advantage makes Wegovy more convenient for travel or situations where refrigerated storage is temporarily unavailable. Each FlexTouch pen contains four doses, requiring proper storage throughout the weekly injection schedule. The dose escalation journey requires careful attention to storage requirements as you progress through different strength pens.
Wegovy vs Mounjaro: Choosing Your Dosing Strategy
The question of what are the doses of Wegovy versus Mounjaro extends beyond simple milligram comparisons to fundamental mechanistic differences. Wegovy's semaglutide targets GLP-1 receptors exclusively, whilst Mounjaro's tirzepatide activates both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. This dual mechanism may influence individual response patterns and optimal dosing strategies.
Patient factors including BMI, diabetes status, previous weight loss medication experience, and gastrointestinal sensitivity may guide dose selection between these options. Your prescriber will consider these factors alongside current NICE TA875 guidance for Wegovy and emerging evidence for tirzepatide. Both medications require prescription-only access and specialist weight management support for optimal outcomes.
Complete Your Weight Management Journey
EverydayMeds provides both Wegovy and Mounjaro through our comprehensive weight management service, ensuring you receive the most appropriate dosing strategy for your individual needs. Our GPhC #9012878 registered pharmacy combines clinical expertise with convenient access, supporting your long-term weight management goals. Apply discount codes FIRST40 (new customers) or DOSE25 (returning customers) at checkout to access competitive pricing on both medications. Complete your clinical assessment today at https://everydaymeds.co.uk/collections/weight-loss to begin your prescribed weight management journey. Both medications must be used alongside a reduced-calorie diet and increased physical activity as part of a comprehensive weight management programme.
Reviewed by the EverydayMeds Clinical Team · GPhC #9012878 · Last updated February 2026
