Wegovy or Mounjaro: Complete Decision Guide
The Key Differences
Understanding how these medications differ helps you choose:
Mounjaro (tirzepatide):
• Dual-action: targets GIP and GLP-1 receptors
• Manufacturer: Eli Lilly
• Average weight loss: 15-22%
• Dose range: 2.5mg to 15mg
Wegovy (semaglutide):
• Single-action: targets GLP-1 receptors only
• Manufacturer: Novo Nordisk
• Average weight loss: 12-15%
• Dose range: 0.25mg to 2.4mg
Weight Loss: Mounjaro Wins
Head-to-head, Mounjaro consistently outperforms Wegovy:
Clinical trial results:
• Mounjaro (SURMOUNT trials): Up to 22.5% weight loss
• Wegovy (STEP trials): Up to 15% weight loss
Real-world difference:
• For a 100kg patient on Mounjaro: 15-22kg potential loss
• For a 100kg patient on Wegovy: 12-15kg potential loss
That's an extra 3-7kg weight loss choosing Mounjaro over Wegovy.
How Each Works
Why Mounjaro works better:
Mounjaro's dual action means two pathways working together:
• GLP-1: Reduces appetite, slows digestion, increases fullness
• GIP: Enhances metabolic response, amplifies weight loss effect
Why Wegovy is still effective:
Wegovy's GLP-1 action alone still delivers meaningful results:
• Proven appetite reduction
• Significant weight loss for many patients
• Well-established safety profile
Both work - Mounjaro simply works better for most people.
Side Effect Comparison
Both medications have similar side effect profiles:
Common with both:
• Nausea (especially initially)
• Digestive changes
• Reduced appetite
• Injection site reactions (mild)
Neither has significantly worse side effects than the other. Both improve with gradual dose titration.
UK Availability
Mounjaro: Good UK availability through online pharmacies like EverydayMeds
Wegovy: Supply has been inconsistent in the UK due to manufacturing constraints
Mounjaro currently offers more reliable access for UK patients.
Price Comparison
Mounjaro at EverydayMeds: From £129.99 with code FIRST40
Wegovy typical UK price: £150-300 (when available)
Mounjaro offers better results at a competitive price point.
Making Your Choice
Choose Mounjaro if:
• Maximum weight loss is your goal
• You want the most clinically effective option
• You prefer reliable UK availability
• You're new to weight loss injections
Consider Wegovy if:
• You've had excellent results with semaglutide before
• Your doctor specifically recommends it
• You have specific reasons to prefer this medication
For most patients, Mounjaro is the evidence-based choice.
Get Mounjaro Today
Made your decision? Order Mounjaro from EverydayMeds using code FIRST40 for £40 off. From £129.99 with next-day delivery.
