Complete Wegovy vs Mounjaro Dosing Comparison
Wegovy Dosage Chart vs Mounjaro: Understanding the Key Differences
The wegovy dosage chart reveals a carefully structured five-dose escalation over 16 weeks, whilst Mounjaro employs six doses across a similar timeframe. Wegovy begins at 0.25mg weekly, progressing through 0.5mg, 1mg, 1.7mg, to maintenance at 2.4mg, with each dose sustained for four weeks. Mounjaro starts higher at 2.5mg, escalating every four weeks through 5mg, 7.5mg, 10mg, 12.5mg, reaching 15mg maintenance. This fundamental difference reflects their distinct mechanisms—Wegovy's semaglutide targets GLP-1 receptors exclusively, whilst Mounjaro's tirzepatide activates both GLP-1 and GIP receptors. Both are prescription-only medicines requiring clinical assessment and must be used alongside a reduced-calorie diet and increased physical activity.
Understanding the wegovy dosage chart versus Mounjaro's schedule helps patients and prescribers choose the most suitable option. Wegovy's lower starting dose may benefit those concerned about initial side effects, with gradual 4-weekly increases allowing careful tolerance monitoring. Mounjaro's higher starting point reflects its dual-hormone mechanism, requiring different dose calibration for optimal efficacy. Neither approach is inherently superior—the choice depends on individual patient factors, medical history, and prescriber assessment. EverydayMeds' clinical team can guide patients through both options during the online assessment process.
UK Pricing Comparison: Wegovy vs Mounjaro Cost Analysis
EverydayMeds offers transparent pricing for both treatments, with the wegovy dosage chart showing costs from £79.99 for the 0.25mg starter dose to £209.99 for 2.4mg maintenance. New customers apply code FIRST40 at checkout, whilst returning customers use DOSE25 to reach these final prices. The complete Wegovy escalation costs £524.95 individually (0.25mg through 2.4mg), though convenient bundles like the Intro Trio (0.25mg, 0.5mg, 1mg) cost £299.99. Each pen provides four weekly injections, making the cost per injection £19.99 at starter level, increasing with dose strength.
Mounjaro pricing follows a similar premium structure, with both treatments representing significant monthly investments requiring careful consideration. Bundle options provide convenience rather than savings—the Consistency 2.4mg bundle (×2 pens) costs £419.99, ensuring two months of maintenance supply without reordering. Express prescriber review adds convenience for urgent requirements, though standard three-day review suffices for most patients. Both treatments qualify for next-day delivery once approved, with temperature-controlled packaging ensuring product integrity throughout the UK.
Clinical Evidence: STEP Trials and Wegovy Dosage Chart Efficacy
The wegovy dosage chart's effectiveness was demonstrated across the STEP trial programme, with patients taking Wegovy alongside diet and exercise achieving approximately 15% average weight loss at 68 weeks compared to 2.4% with placebo (Wilding et al., NEJM, 2021). STEP 2 showed 9.6% weight reduction in patients with type 2 diabetes, whilst STEP 3 demonstrated 16% loss when combined with intensive behavioural therapy. The recent SELECT trial revealed a 20% reduction in major cardiovascular events, highlighting benefits beyond weight management.
Mounjaro's SURMOUNT trials showed different outcomes, though direct comparison isn't appropriate due to varying trial designs and patient populations. Both treatments demonstrated efficacy when used as prescribed, with the wegovy dosage chart's gradual escalation supporting sustained weight management over extended periods. STEP 5 confirmed clinically studied weight loss sustained at two years, emphasising long-term commitment requirements. All clinical evidence frames outcomes as averages—individual results vary considerably based on adherence, lifestyle factors, and underlying health conditions.
How Wegovy Works: GLP-1 Mechanism Explained
Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics the natural hormone released when food enters the intestine. This mechanism reduces appetite by signalling fullness to brain appetite centres, promoting satiety after smaller meals and potentially reducing food cravings throughout the day. The wegovy dosage chart's graduated approach allows the body to adapt to increasing GLP-1 activity whilst minimising side effects. Unlike rapid-acting appetite suppressants, Wegovy works gradually to reset eating patterns and portion control naturally. Weekly injections maintain steady hormone levels, providing consistent appetite regulation between doses whilst supporting sustainable lifestyle changes required for long-term weight management success.
EverydayMeds Ordering Process: From Assessment to Delivery
Obtaining Wegovy through EverydayMeds begins with a three-minute online clinical assessment covering medical history, current medications, weight management goals, and contraindication screening. Our UK-registered prescribers (GPhC #9012878) review applications within three working days, or 24 hours with express service, ensuring thorough safety evaluation before approval. Approved orders receive next-day delivery via temperature-controlled courier, maintaining the 2-8°C cold chain required for medication integrity. Patients receive injection training materials, sharps disposal containers, and access to ongoing clinical support throughout their treatment journey. The wegovy dosage chart guidance helps patients track their escalation schedule and plan future orders accordingly.
Storage Requirements and Practical Considerations
The wegovy dosage chart must account for proper storage to maintain medication effectiveness—unused pens require refrigeration at 2-8°C until first use. Once removed from refrigeration, Wegovy remains stable for up to six weeks at room temperature below 30°C, offering significant travel advantages over Mounjaro's 21-day limit. FlexTouch pens provide precise dosing with clear dose windows and audible click confirmation when injection completes. Patients inject subcutaneously into thigh, abdomen, or upper arm, rotating sites weekly to prevent lipodystrophy. The prescription-only medicine requires careful handling—patients should never share pens, freeze medication, or use expired products regardless of apparent condition.
Wegovy Dosage Chart vs Mounjaro: Escalation Timeline Comparison
The wegovy dosage chart's 16-week escalation contrasts with Mounjaro's similar timeframe but different milligram progression, reflecting their distinct pharmacological profiles. Wegovy patients spend four weeks each at 0.25mg, 0.5mg, 1mg, and 1.7mg before reaching 2.4mg maintenance, allowing gradual tolerance development. This measured approach suits patients preferring conservative dose increases, particularly those with previous GLP-1 experience or gastric sensitivity concerns. Mounjaro's 2.5mg starting dose reflects tirzepatide's dual-hormone mechanism requiring different calibration for therapeutic effect.
Both escalation schedules are mandatory—patients cannot skip doses or accelerate progression without prescriber approval, as rushing increases side effect risks whilst potentially compromising long-term adherence. The wegovy dosage chart provides clear progression milestones, helping patients understand their treatment timeline and plan accordingly. EverydayMeds stocks all doses continuously, ensuring seamless progression without treatment interruptions that could necessitate restarting at lower doses.
Choose Your Treatment: Expert Prescriber Guidance Available
EverydayMeds offers both Wegovy and Mounjaro, providing patients access to leading weight management treatments through one trusted UK pharmacy. Our clinical assessment process evaluates individual suitability for either option, considering medical history, lifestyle factors, and patient preferences alongside clinical guidelines. The wegovy dosage chart suits patients preferring lower starting doses with gradual escalation, whilst Mounjaro may benefit those requiring dual-hormone stimulation. Both are prescription-only medicines requiring ongoing medical supervision and lifestyle commitment for optimal outcomes. New customers use code FIRST40 whilst returning customers apply DOSE25 at checkout to access our competitive pricing structure. Visit https://everydaymeds.co.uk/collections/weight-loss to begin your clinical assessment today and discover which treatment aligns with your weight management goals.
Reviewed by the EverydayMeds Clinical Team · GPhC #9012878 · Last updated February 2026
