Detailed Comparison: Sildenafil vs Avanafil
How These ED Medications Work
Both Viagra (sildenafil) and Spedra (avanafil) belong to a class of medications called PDE5 inhibitors. They work by blocking the phosphodiesterase type 5 enzyme, which increases blood flow to the penis when sexually aroused. Neither medication causes automatic erections - sexual stimulation is still required for effectiveness.
Speed of Action and Duration
The main difference between these treatments lies in their onset times. Viagra containing sildenafil typically becomes effective within 30-60 minutes of taking the tablet. Spedra, containing avanafil, may work slightly faster, potentially within 15-30 minutes for some patients.
Both medications can remain effective for 4-6 hours, though this doesn't mean an erection will last this long. The duration refers to the window during which the medication can help achieve erections when sexually stimulated.
Food and Alcohol Interactions
Spedra generally shows less interaction with food compared to Viagra. High-fat meals can delay Viagra's effectiveness, whilst Spedra may be less affected by food intake. Both medications can be affected by excessive alcohol consumption, which may reduce their effectiveness and increase the risk of side effects like dizziness or low blood pressure.
Dosage Options Available
Viagra and generic sildenafil are available in 25mg, 50mg, and 100mg strengths. The typical starting dose is 50mg, which can be adjusted based on effectiveness and tolerability. Spedra comes in 50mg, 100mg, and 200mg tablets, with 100mg being the usual starting dose.
Cost Considerations
Viagra is the original branded version of sildenafil, whilst generic sildenafil contains the same active ingredient at a lower cost. At EverydayMeds, patients can choose between branded Viagra or generic sildenafil during checkout after completing their consultation. This flexibility allows patients to select based on their preferences and budget whilst receiving the same clinical benefits.
Side Effects Profile
Both medications share similar common side effects, including headaches, facial flushing, nasal congestion, and indigestion. Some studies suggest Spedra may have a slightly lower incidence of certain side effects, but individual responses vary significantly.
Eligibility and Consultation Process
Both treatments require consultation with a UK-licensed prescriber to ensure they're suitable for your health status and current medications. Patients with heart conditions, those taking nitrate medications, or with certain medical histories may not be suitable candidates for either treatment.
The consultation process at EverydayMeds evaluates your medical history, current medications, and overall cardiovascular health to determine the most appropriate treatment option.












