Orlistat vs Saxenda: Compare Prescription Weight Loss UK

pricing for mounjaro and wegovy weight loss

Choosing between orlistat and Saxenda for prescription weight loss in the UK? Both require clinical assessment, but work differently. Orlistat 120mg blocks approximately one third of dietary fat absorption, starting from £29.69 for 4 weeks with code EDM10. Saxenda is an injectable GLP-1 agonist that affects appetite regulation. Orlistat works locally in the gut alongside a reduced-calorie, lower-fat diet, while Saxenda requires daily injections. Generic orlistat offers excellent value compared to branded alternatives. Complete an online clinical assessment today to see which prescription weight loss treatment may be suitable for you.

  • Orlistat from £29.69/month with EDM10 discount code
  • Clinical assessment by UK-licensed prescriber included
  • Next day delivery from GPhC-registered pharmacy
  • Works alongside reduced-calorie, lower-fat diet plan
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Prescription Weight Loss Treatment Suits You?

Orlistat vs Saxenda: How They Work Differently

Orlistat and Saxenda represent two distinct approaches to prescription weight loss in the UK. Orlistat 120mg works by inhibiting lipase enzymes in your digestive system, blocking approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body. Saxenda (liraglutide) is an injectable GLP-1 receptor agonist that affects appetite regulation through the brain. Both require clinical assessment and work best alongside lifestyle changes.

Orlistat Prescription Options and Pricing

EverydayMeds offers three orlistat options following online clinical assessment. Generic orlistat 120mg provides excellent value at £32.99 for 4 weeks (£29.69 with EDM10). Branded Xenical contains identical orlistat 120mg at £42.99 for 4 weeks (£38.69 with EDM10). Alli 60mg offers half-strength dosing at £28.99 for 4 weeks (£26.09 with EDM10). All options require taking one capsule with each main meal containing fat, up to three times daily.

Key Differences: Oral vs Injectable Treatment

The primary difference lies in administration method and mechanism. Orlistat capsules are taken orally with meals, working locally in your gut without significant absorption into your bloodstream. Saxenda requires daily subcutaneous injections, working systemically through appetite regulation. Many patients prefer orlistat's oral convenience and lower cost. Others may find injection-based treatments more suitable for their circumstances.

Cost Comparison and Value Considerations

Orlistat typically offers more affordable prescription weight loss treatment. Our generic orlistat 120mg costs £29.69 monthly with EDM10, compared to significantly higher Saxenda costs. Both require ongoing clinical monitoring and lifestyle support. The 12-week orlistat supply at £86.39 with EDM10 provides substantial savings for longer-term treatment plans.

Suitability and Clinical Assessment Process

Both treatments require individual clinical assessment by UK-licensed prescribers. Orlistat may be suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Saxenda has similar BMI criteria but different contraindications and monitoring requirements. Complete our online health questionnaire for professional review of your treatment options. Your prescriber will determine the most appropriate option based on your medical history, current medications, and treatment goals.

Side Effect Profiles and Management

Orlistat's side effects are primarily gastrointestinal, including oily stools, urgent bowel movements, and flatulence with discharge. These effects relate directly to dietary fat intake and can be minimised by maintaining low-fat meals (approximately 15g fat per meal). Saxenda's side effects include nausea, vomiting, diarrhoea, and potential injection site reactions. Both medications require careful monitoring and lifestyle adjustments for optimal results.

Order Your Prescription Weight Loss Treatment Today

Ready to start your prescription weight loss journey? Complete an online clinical assessment to compare orlistat and Saxenda options. Our UK-licensed prescribers will review your suitability for both treatments and recommend the most appropriate choice. All medications are dispensed by our GPhC-registered Leicester pharmacy with next day delivery available. Use code EDM10 for 10% off every order, whether you choose orlistat, Xenical, or alternative treatments.

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