Which Prescription Weight Loss Treatment Suits You?
Orlistat vs Saxenda: How They Work Differently
Orlistat and Saxenda represent two distinct approaches to prescription weight loss in the UK. Orlistat 120mg works by inhibiting lipase enzymes in your digestive system, blocking approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body. Saxenda (liraglutide) is an injectable GLP-1 receptor agonist that affects appetite regulation through the brain. Both require clinical assessment and work best alongside lifestyle changes.
Orlistat Prescription Options and Pricing
EverydayMeds offers three orlistat options following online clinical assessment. Generic orlistat 120mg provides excellent value at £32.99 for 4 weeks (£29.69 with EDM10). Branded Xenical contains identical orlistat 120mg at £42.99 for 4 weeks (£38.69 with EDM10). Alli 60mg offers half-strength dosing at £28.99 for 4 weeks (£26.09 with EDM10). All options require taking one capsule with each main meal containing fat, up to three times daily.
Key Differences: Oral vs Injectable Treatment
The primary difference lies in administration method and mechanism. Orlistat capsules are taken orally with meals, working locally in your gut without significant absorption into your bloodstream. Saxenda requires daily subcutaneous injections, working systemically through appetite regulation. Many patients prefer orlistat's oral convenience and lower cost. Others may find injection-based treatments more suitable for their circumstances.
Cost Comparison and Value Considerations
Orlistat typically offers more affordable prescription weight loss treatment. Our generic orlistat 120mg costs £29.69 monthly with EDM10, compared to significantly higher Saxenda costs. Both require ongoing clinical monitoring and lifestyle support. The 12-week orlistat supply at £86.39 with EDM10 provides substantial savings for longer-term treatment plans.
Suitability and Clinical Assessment Process
Both treatments require individual clinical assessment by UK-licensed prescribers. Orlistat may be suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Saxenda has similar BMI criteria but different contraindications and monitoring requirements. Complete our online health questionnaire for professional review of your treatment options. Your prescriber will determine the most appropriate option based on your medical history, current medications, and treatment goals.
Side Effect Profiles and Management
Orlistat's side effects are primarily gastrointestinal, including oily stools, urgent bowel movements, and flatulence with discharge. These effects relate directly to dietary fat intake and can be minimised by maintaining low-fat meals (approximately 15g fat per meal). Saxenda's side effects include nausea, vomiting, diarrhoea, and potential injection site reactions. Both medications require careful monitoring and lifestyle adjustments for optimal results.
Order Your Prescription Weight Loss Treatment Today
Ready to start your prescription weight loss journey? Complete an online clinical assessment to compare orlistat and Saxenda options. Our UK-licensed prescribers will review your suitability for both treatments and recommend the most appropriate choice. All medications are dispensed by our GPhC-registered Leicester pharmacy with next day delivery available. Use code EDM10 for 10% off every order, whether you choose orlistat, Xenical, or alternative treatments.


