Why Choose Prescription Weight Loss Treatment?
Understanding Prescription Weight Loss Options
Prescription weight loss medications like orlistat 120mg work by blocking approximately one third of dietary fat absorption in the gut. This lipase inhibitor approach may help support weight management when combined with a reduced-calorie, lower-fat diet and increased physical activity. Following clinical assessment by a UK-licensed prescriber, orlistat may be suitable for adults with a BMI of 30 or above, or 28 and above with weight-related health conditions.
Orlistat Pricing and Pack Sizes
Our generic orlistat 120mg starts from £16.89 for 2 weeks (42 capsules), reduced to £15.20 with code EDM10. For longer treatment periods, 4-week supplies cost £32.99 (£29.69 with discount), 8-week supplies £63.99 (£57.59), and 12-week supplies £95.99 (£86.39). Branded Xenical 120mg is also available, containing the same active ingredient at identical clinical strength.
Combination Treatment Considerations
Some patients enquire about using orlistat alongside other prescription weight loss treatments. Any combination approach requires careful medical supervision and individual assessment by qualified healthcare professionals. Your prescriber will evaluate whether multiple treatments are appropriate based on your health profile, current medications, and weight management goals. Never combine prescription medications without explicit medical guidance.
How Orlistat Works
Orlistat inhibits lipase enzymes in the digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through the body, potentially reducing calorie intake from dietary fat. The medication works locally in the gut rather than affecting the brain or central nervous system. Effects are directly related to meal fat content - lower fat meals typically result in fewer gastrointestinal side effects.
Clinical Assessment Process
Complete our confidential online health questionnaire covering medical history, current medications, BMI, and weight management goals. A UK-licensed prescriber reviews your information and determines treatment suitability. If appropriate, your prescription is issued and dispensed by our GPhC-registered Leicester pharmacy. Medication is dispatched with tracked, discreet delivery across the UK, typically arriving next working day.
Supporting Your Weight Management Journey
Prescription weight loss medication works best as part of a comprehensive approach including dietary modification, increased physical activity, and behavioural support. Orlistat requires commitment to a lower-fat diet (approximately 30% of calories from fat, roughly 15g per meal) to minimise side effects and optimise effectiveness. A daily multivitamin taken at bedtime is recommended to support fat-soluble vitamin absorption.


