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Prescription Weight Loss Treatment - Orlistat & Xenical 120mg
Orlistat and Xenical 120mg capsules are prescription-only medicines designed to support weight management in adults with obesity or significant overweight with health risks. Both contain the same active ingredient - orlistat - which works by blocking approximately one third of dietary fat absorption in the gut. Following clinical assessment by our UK-licensed prescribers, these treatments may help support your weight loss goals alongside a reduced-calorie, lower-fat diet and increased physical activity.
How Prescription Orlistat Works
Orlistat works locally in your digestive system by inhibiting lipase enzymes that break down dietary fat. When these enzymes are blocked, approximately one third of the fat you eat cannot be absorbed and passes naturally through your body. This mechanism may help reduce calorie intake from dietary fat as part of a structured weight management programme. The medication works best when combined with meals containing no more than 15g fat per meal to minimise side effects.
Generic Orlistat vs Branded Xenical - Same Effect, Different Price
Our pharmacy stocks both generic Orlistat 120mg and branded Xenical 120mg capsules. Both contain identical active ingredients at the same dose and provide equivalent clinical effects. The key difference is cost - generic Orlistat offers significant savings whilst delivering the same fat-blocking action. Orlistat 120mg 4-week supply costs £32.99 (£29.69 with EDM10), whilst Xenical 120mg 4-week supply costs £42.99 (£38.69 with EDM10). Choose based on your preference and budget - both require prescription following clinical assessment.
Available Pack Sizes and Pricing
We offer flexible supply options to suit your treatment duration. Generic Orlistat 120mg: 2-week supply (42 capsules) £16.89, 4-week supply (84 capsules) £32.99, 8-week supply (168 capsules) £63.99, and 12-week supply (252 capsules) £95.99. Branded Xenical 120mg: 2-week supply £21.50, 4-week supply £42.99, 8-week supply £86.99, and 12-week supply £128.99. Apply code EDM10 for 10% off all orders. Lower-strength Alli 60mg also available without prescription for those preferring a gentler starting option.
Online Clinical Assessment Process
Accessing prescription weight loss treatment through our GPhC-registered pharmacy is straightforward. Complete our confidential online health questionnaire covering your medical history, current medications, and weight management goals. A qualified UK-licensed prescriber will review your information and assess suitability for Orlistat or Xenical treatment. If appropriate, your prescription will be issued and your medication dispensed by our Leicester-based pharmacy team for next day delivery across the UK.
Who May Be Suitable for Prescription Orlistat
Orlistat 120mg may be suitable for adults aged 18 or over with a BMI of 30 kg/m² or above, or those with a BMI of 28 kg/m² or above with weight-related health conditions such as type 2 diabetes, high blood pressure, or high cholesterol. Treatment suitability depends on individual circumstances and medical history. Our prescribers will assess whether prescription weight loss treatment is appropriate based on your consultation responses.
Important Safety Information
Like all prescription medicines, Orlistat and Xenical may cause side effects. Most are gastrointestinal and directly related to dietary fat intake - keeping meals low in fat significantly reduces side effects. Common effects include oily stools, increased bowel frequency, and oily spotting. These effects indicate the medication is working by preventing fat absorption. A daily multivitamin taken at bedtime is recommended as orlistat may reduce absorption of fat-soluble vitamins. Always follow your prescriber's guidance and report any concerning symptoms.


