Compare Prescription Weight Loss Options Available
Orlistat vs Semaglutide: Understanding Your Prescription Weight Loss Options
When considering prescription weight loss treatment in the UK, orlistat and semaglutide represent two different approaches. Orlistat 120mg capsules work by blocking approximately one third of dietary fat absorption in your digestive system, whilst semaglutide is an injectable medication that affects appetite regulation. Both require clinical assessment and prescription from qualified healthcare professionals.
Orlistat 120mg: How It May Support Weight Management
Orlistat works locally in your gut by inhibiting lipase enzymes responsible for breaking down dietary fat. This means approximately one third of the fat you eat cannot be absorbed and passes naturally through your body. Available as generic orlistat from £16.89 for 42 capsules (2-week supply) or branded Xenical from £21.50, both containing identical active ingredients at the same 120mg dose.
Prescription Weight Loss Pricing at EverydayMeds
Generic orlistat 120mg offers excellent value: 4-week supply (84 capsules) costs £32.99, reduced to £29.69 with code EDM10. For longer treatment, 12-week supplies (252 capsules) are £95.99, or £86.39 with discount. Branded Xenical 120mg provides the same clinical effect at £42.99 for 84 capsules (£38.69 with EDM10). All prices include the prescription following successful clinical assessment.
Who May Be Suitable for Prescription Orlistat
Orlistat may be suitable for adults with a BMI of 30 kg/m² or above, or 28 kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure. Treatment suitability is assessed individually through our online clinical consultation, reviewed by UK-licensed prescribers. Orlistat must always be used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Online Clinical Assessment Process
Complete our confidential health questionnaire covering your medical history, current medications, and weight management goals. A qualified UK prescriber reviews your information to determine if prescription weight loss treatment is clinically appropriate. If approved, your orlistat is dispensed by our GPhC-registered pharmacy and delivered discreetly to your address with next day delivery available.
Important Safety Information
Like all prescription medicines, orlistat may cause side effects, particularly gastrointestinal effects when eating high-fat meals. Keeping meals low in fat (approximately 15g per meal) helps minimise side effects significantly. Most side effects reduce as your diet adapts. A daily multivitamin taken at bedtime is recommended as orlistat may reduce absorption of fat-soluble vitamins.


