Is Orlistat Available OTC? UK Prescription Options

pricing for mounjaro and wegovy weight loss

Orlistat 120mg is prescription-only in the UK, not available over-the-counter. Following an online clinical assessment by a UK-licensed prescriber, you can access orlistat through EverydayMeds' GPhC-registered pharmacy. Generic orlistat 120mg starts from £29.69 for 4 weeks with code EDM10, while branded Xenical costs £38.69. Alli 60mg offers a lower-strength option at £26.09. All treatments work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Complete your confidential assessment today to see if prescription weight loss treatment is right for you.

  • Prescription orlistat 120mg from £29.69 (4 weeks) with EDM10 discount
  • Online clinical assessment by UK-licensed prescribers
  • Next day delivery from GPhC-registered Leicester pharmacy
  • Choice of generic orlistat, branded Xenical, or Alli 60mg
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Is Orlistat Available Over-the-Counter in the UK?

Orlistat 120mg is prescription-only medicine in the UK and cannot be purchased over-the-counter. This includes both generic orlistat 120mg and branded Xenical 120mg. However, Alli 60mg (half-strength) is available without prescription. For the full prescription strength that may be more effective for weight management, you need a clinical assessment and prescription from a qualified UK healthcare professional.

Prescription Orlistat vs OTC Alli

Prescription orlistat 120mg blocks approximately one third of dietary fat absorption, while Alli 60mg (available OTC) contains half the dose. Both work by inhibiting lipase enzymes in the gut, but prescription strength may provide better support for weight management when used alongside a reduced-calorie, lower-fat diet. Generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), while Alli 60mg costs £54.99 for 8 weeks (£49.49 with EDM10).

Online Prescription Service

EverydayMeds offers convenient access to prescription orlistat through regulated online consultation. Complete a confidential health questionnaire reviewed by UK-licensed prescribers who assess your suitability based on BMI, medical history, and weight-related health factors. If approved, your prescription is dispensed by our GPhC-registered pharmacy in Leicester with next day delivery across the UK.

Treatment Options Available

Choose from three clinically proven options: Generic orlistat 120mg offers the most cost-effective prescription treatment, starting at £16.89 for 2 weeks (£15.20 with EDM10). Branded Xenical 120mg contains identical active ingredient at £21.50 for 2 weeks (£19.35 with EDM10). For longer treatment, 12-week supplies cost £95.99 for generic orlistat or £128.99 for Xenical. All treatments work best when fat intake is limited to approximately 15g per meal.

How Prescription Orlistat Works

Orlistat works locally in your digestive system by blocking lipase enzymes that break down dietary fat. This prevents approximately one third of fat from meals being absorbed into your body. The unabsorbed fat passes naturally through your system. Unlike appetite suppressants, orlistat doesn't affect your brain or nervous system. It works most effectively when combined with a structured weight management programme including reduced-calorie, lower-fat diet and increased physical activity.

Who May Be Suitable

Prescription orlistat may be suitable for adults with BMI of 30 kg/m² or above, or BMI 28 kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure. Suitability is determined through individual clinical assessment. Treatment is not suitable for everyone - those who are pregnant, breastfeeding, under 18, or have certain medical conditions should not use orlistat. Your prescriber will review your complete medical history before making prescribing decisions.

Start Your Assessment Today

Ready to explore prescription weight loss treatment? Complete our confidential online assessment to see if orlistat is right for you. With 10% off every order using code EDM10, prescription treatment is more affordable than you might expect. All medication is sourced through licensed UK pharmaceutical supply chains and delivered discreetly to your address. Take the first step towards supported weight management today.

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