Understanding Orlistat Side Effects Before You Buy
Can Orlistat Cause Stomach Cramps?
Yes, stomach cramps are a recognised side effect of orlistat treatment. Abdominal pain or discomfort affects more than 1 in 10 people taking this prescription weight loss medication. These symptoms occur because orlistat blocks approximately one third of dietary fat from being absorbed, leading to undigested fat passing through your digestive system.
Why Do Stomach Cramps Happen With Orlistat?
Orlistat works by inhibiting lipase enzymes in your gut, preventing the breakdown and absorption of dietary fat. When you eat a high-fat meal, more unabsorbed fat travels through your intestines, potentially causing cramping, urgency, and other gastrointestinal effects. The severity typically correlates with the fat content of your meals.
Minimising Stomach Cramps While Taking Orlistat
You can significantly reduce stomach cramps by keeping each meal to approximately 15g of fat or less. Spreading your daily fat intake evenly across three main meals helps prevent the digestive overload that triggers cramping. Most patients find symptoms improve within the first few weeks as they adapt their diet and the medication begins working effectively.
Orlistat Pricing and Options at EverydayMeds
We offer three prescription weight loss options following clinical assessment. Generic orlistat 120mg provides excellent value at £32.99 for 4 weeks (£29.69 with EDM10). Branded Xenical 120mg costs £42.99 for 4 weeks (£38.69 with EDM10). For those preferring a lower-strength option, Alli 60mg is available at £28.99 for 4 weeks (£26.09 with EDM10).
When to Seek Medical Advice
Contact your prescriber if stomach cramps become severe, persistent, or are accompanied by dark urine, yellowing of skin/eyes, or signs of dehydration. Severe abdominal pain could indicate rare but serious complications requiring immediate medical attention. Our UK-licensed prescribers are available to discuss any concerns about your treatment.
Complete Your Clinical Assessment Today
Ready to start your prescription weight loss journey? Complete our online clinical assessment to determine if orlistat is suitable for you. Following prescriber approval, your medication will be dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address with next-day delivery available across the UK.


