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What Are Orlistat and Xenical Tablets Used For?
Orlistat and Xenical tablets are prescription-only weight loss medications designed to support weight management in adults. Both contain orlistat 120mg, a lipase inhibitor that works by blocking approximately one third of the fat you eat from being absorbed into your body. The unabsorbed fat passes naturally through your digestive system, helping reduce calorie intake from dietary fat when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
These medications may be suitable for adults with a BMI of 30 kg/m² or above, or those with a BMI of 28 kg/m² or above with weight-related health conditions such as type 2 diabetes or high blood pressure. A clinical assessment by a qualified UK prescriber is required to determine suitability.
Generic Orlistat vs Branded Xenical - Which Should You Choose?
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and provide the same clinical effect. The key difference is cost - generic orlistat offers significant savings whilst delivering equivalent weight management support. Our 4-week supply of generic orlistat costs £29.69 with EDM10, compared to £38.69 for branded Xenical, saving you approximately £9 per month.
Generic orlistat 120mg is available from £15.20 per fortnight (42 capsules), £29.69 for 4 weeks (84 capsules), £57.59 for 8 weeks (168 capsules), and £86.39 for 12 weeks (252 capsules) when you use discount code EDM10. Xenical pricing starts from £19.35 per fortnight with the same discount applied.
How Do Orlistat Tablets Work for Weight Loss?
Orlistat works locally in your digestive system by inhibiting lipase enzymes responsible for breaking down dietary fat. When these enzymes are blocked, approximately one third of the fat from your meals cannot be digested or absorbed, instead passing through your body naturally. This mechanism helps reduce your overall calorie intake from fat, supporting weight management when combined with appropriate dietary and lifestyle changes.
The medication is most effective when taken as one 120mg capsule three times daily with each main meal containing fat. If you skip a meal or eat a meal with no fat, you can omit that dose. For optimal results and to minimise side effects, keep your fat intake to approximately 15g per meal spread evenly throughout the day.
Online Prescription Process - Fast, Discreet, Professional
Getting your prescription weight loss treatment through EverydayMeds is straightforward and convenient. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber will review your information and, where clinically appropriate, issue a prescription for orlistat or Xenical.
Once approved, your medication is dispensed by our GPhC-registered pharmacy in Leicester and dispatched with next day delivery across the UK. All packaging is discreet and secure, with the prescription cost included - no separate GP appointment required. Use code EDM10 at checkout for 10% off every order, available to both new and returning customers.
Important Safety Information and Side Effects
Like all prescription medicines, orlistat may cause side effects, particularly gastrointestinal ones related to the unabsorbed fat passing through your system. Common side effects include oily or fatty stools, oily spotting, urgent bowel movements, and abdominal discomfort. These effects are more likely when eating high-fat meals and typically reduce as you adapt to a lower-fat diet.
Most side effects can be minimised by keeping your fat intake low and evenly distributed across meals. Orlistat may reduce absorption of fat-soluble vitamins (A, D, E, K), so taking a daily multivitamin at bedtime is recommended. Always follow your prescriber's guidance and seek medical advice if you experience severe or persistent side effects.


