Compare Orlistat and Mounjaro for Weight Loss
How Orlistat and Mounjaro Work Differently
Orlistat and Mounjaro represent two distinct approaches to prescription weight loss in the UK. Orlistat works locally in your digestive system as a lipase inhibitor, blocking approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body. Mounjaro (tirzepatide) is an injectable GLP-1 receptor agonist that works differently, affecting hormones that regulate blood sugar and appetite.
Orlistat is taken as capsules three times daily with meals containing fat, while Mounjaro requires weekly injections. Both treatments require prescription following clinical assessment by a UK-licensed prescriber and work best alongside a reduced-calorie diet and increased physical activity.
Orlistat Options and Pricing at EverydayMeds
We offer three orlistat options to suit different needs and budgets. Generic orlistat 120mg provides the most cost-effective prescription-strength option from £15.20 for 2 weeks with code EDM10. Our 4-week supply costs £29.69 with discount, while 12-week supplies are £86.39 with EDM10.
Branded Xenical 120mg contains identical active ingredient but costs slightly more at £19.35 for 2 weeks with EDM10. Some patients prefer the branded option, while others choose generic orlistat for better value. Alli 60mg offers a lower-strength option at £26.09 for 4 weeks with code EDM10.
Eligibility and Assessment Process
Orlistat may be suitable for adults with BMI of 30 kg/m² or above, or BMI of 28 kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure. Mounjaro has different eligibility criteria and is typically reserved for specific clinical situations. Both require individual clinical assessment.
Our online consultation process makes accessing orlistat straightforward. Complete your health questionnaire, receive prescriber review, and get next-day delivery if treatment is deemed appropriate. No separate GP appointment needed - prescription included in the price.
Side Effects and Considerations
Orlistat's side effects are mainly gastrointestinal and directly related to dietary fat intake. Common effects include oily stools, increased bowel movements, and urgent need for the toilet. These can be minimised by keeping meals low in fat (approximately 15g per meal). Most side effects reduce as your diet adapts.
Mounjaro's side effects are different, commonly including nausea, vomiting, and digestive issues, but through different mechanisms. Your prescriber will discuss which treatment's side effect profile may be more suitable for your circumstances.
Start Your Clinical Assessment Today
Ready to explore prescription weight loss options? Begin with our online clinical assessment to determine if orlistat is suitable for you. Our UK-licensed prescribers will review your information and, if appropriate, issue a prescription for dispatch from our GPhC-registered Leicester pharmacy. Use code EDM10 for 10% off your first and all future orders.


