Orlistat and Metformin: Safe Combination Treatment
Taking Orlistat with Metformin: Clinical Assessment
Orlistat and metformin can typically be prescribed together as they work through different mechanisms. Orlistat blocks approximately one third of dietary fat absorption in the gut, while metformin helps regulate blood sugar levels. During your online consultation, our UK-licensed prescribers will review all current medications including metformin to ensure treatment safety. Individual clinical assessment determines whether this combination is appropriate for your specific health circumstances.
Why Choose Orlistat for Weight Management?
Orlistat 120mg is a prescription-only weight loss medication that may help support weight management when used alongside a reduced-calorie, lower-fat diet. Generic orlistat offers excellent value at £32.99 for 4 weeks (£29.69 with EDM10), while branded Xenical 120mg is available for £42.99 (£38.69 with EDM10). Both contain identical active ingredients and provide the same clinical effect - the key difference is cost.
How Our Online Prescription Service Works
Complete your medical questionnaire including details of current metformin therapy and any other medications. Our UK-licensed prescriber reviews your information and assesses whether orlistat is suitable alongside your existing treatment. If approved, your prescription is dispensed by our GPhC-registered pharmacy in Leicester with next day delivery across the UK. The prescription is included in the price - no separate GP appointment required.
Orlistat Pricing and Pack Sizes
We offer flexible treatment durations to suit your needs. Orlistat 120mg: 2 weeks (42 capsules) £16.89, 4 weeks (84 capsules) £32.99, 8 weeks (168 capsules) £63.99, or 12 weeks (252 capsules) £95.99. Use code EDM10 for 10% off every order. Lower-strength Alli 60mg is also available for those preferring a gentler starting option. All prices include prescription, clinical assessment, and discreet delivery.
Managing Both Medications Effectively
When taking orlistat with metformin, maintain your prescribed metformin schedule as directed by your healthcare provider. Take orlistat capsules with each main meal containing fat - one capsule three times daily. The reduced-calorie, lower-fat diet required for orlistat may also support better blood sugar management alongside metformin therapy. Regular monitoring with your healthcare team remains important for optimal treatment outcomes.


