Compare Orlistat vs Xenical Prices and Choose Your Treatment
Orlistat vs Xenical: The Key Differences
When comparing Orlistat and Xenical for weight loss, the most important fact is that both contain exactly the same active ingredient at the same dose - orlistat 120mg. Orlistat is the generic version, whilst Xenical is the branded version manufactured by Roche. Clinically, they work identically by blocking approximately one third of dietary fat absorption in your digestive system.
The primary difference lies in cost. Generic Orlistat offers significant savings compared to branded Xenical, making it the more economical choice for many patients. Both require a prescription following clinical assessment and work best alongside a reduced-calorie, lower-fat diet.
Orlistat 120mg Pricing and Pack Sizes
Our generic Orlistat 120mg offers excellent value for money across all pack sizes. A 2-week supply (42 capsules) costs £16.89, reduced to £15.20 with code EDM10. For longer treatment periods, a 4-week supply (84 capsules) costs £32.99 or £29.69 with EDM10. Extended 8-week packs (168 capsules) are priced at £63.99, dropping to £57.59 with your discount, whilst 12-week supplies (252 capsules) cost £95.99 or £86.39 with EDM10.
These competitive prices make generic Orlistat accessible for sustained weight management programmes. Take one capsule three times daily with each main meal containing fat, up to a maximum of three capsules per day.
Xenical 120mg Pricing and Branded Option
Branded Xenical 120mg costs more than generic Orlistat but provides the same clinical effect. A 2-week supply (42 capsules) costs £21.50, reduced to £19.35 with EDM10. The 4-week supply (84 capsules) costs £42.99 or £38.69 with your discount code. Longer courses include 8-week packs (168 capsules) at £86.99, dropping to £78.29 with EDM10, and 12-week supplies (252 capsules) priced at £128.99 or £116.09 with discount.
Some patients prefer branded Xenical due to familiarity with the Roche brand, whilst others choose generic Orlistat for better value. Both options undergo the same rigorous clinical assessment process before prescription.
Alli 60mg: Lower-Strength Alternative
Alli 60mg provides a lower-strength option containing half the dose of prescription-strength orlistat. This may suit patients who prefer starting with a milder treatment or experience sensitivity to the full 120mg dose. Alli blocks a smaller proportion of dietary fat compared to prescription-strength options.
Our Alli pricing includes 4-week supplies (42 capsules) at £28.99 or £26.09 with EDM10, 8-week packs (84 capsules) at £54.99 reduced to £49.49, and 12-week supplies (252 capsules) costing £129.99 or £116.99 with discount. Take one capsule three times daily with main meals, following the same timing guidance as prescription-strength versions.
How All Three Options Work
Whether you choose Orlistat, Xenical, or Alli, the mechanism remains consistent - blocking lipase enzymes in your digestive system to prevent fat absorption. Prescription-strength options (Orlistat and Xenical 120mg) block approximately one third of dietary fat, whilst Alli 60mg blocks a smaller proportion due to its lower dose.
Unabsorbed fat passes naturally through your body, which may cause gastrointestinal side effects, particularly when eating high-fat meals. These effects can be minimised by keeping meals low in fat (approximately 15g per meal) and are often a sign the medication is working effectively.
Making Your Choice: Value vs Brand Preference
For most patients, generic Orlistat 120mg represents the best value whilst delivering identical clinical results to branded Xenical. The monthly savings can be substantial - choosing Orlistat over Xenical saves approximately £9 per 4-week supply. Over a 12-week treatment course, you could save nearly £30 by choosing generic over branded.
However, some patients have strong preferences for branded medications or may have been specifically recommended Xenical by their healthcare provider. Both options are dispensed by our GPhC-registered pharmacy following the same rigorous prescription process and clinical standards.
Online Prescription Process
All three options require clinical assessment through our secure online consultation. Complete your medical questionnaire including BMI information, current medications, and weight management history. A UK-licensed prescriber reviews your information and prescribes the most appropriate option if clinically suitable.
Treatment may be suitable for adults with a BMI of 30 or above, or BMI 28 or above with weight-related health conditions. Your prescriber will determine eligibility and recommend whether Orlistat, Xenical, or Alli best suits your individual circumstances. Start your assessment today and get 10% off with EDM10.


