Orlistat vs Xenical: Price Comparison & Buying Guide
What's the Difference Between Orlistat and Xenical?
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Xenical is the original branded version manufactured by Roche, while orlistat is the generic equivalent. They work in precisely the same way - blocking approximately one third of dietary fat absorption in your gut. The clinical effect is identical, making this purely a cost decision.
Price Comparison: Generic vs Branded
Generic orlistat offers significant savings versus branded Xenical. For a 4-week supply (84 capsules), orlistat costs £29.69 with EDM10 compared to Xenical at £38.69 - saving you £9 per month. Over 12 weeks, you save £29.70 by choosing generic orlistat (£86.39) versus Xenical (£116.09). Both prices include the prescription and consultation.
Which Should You Choose?
If cost is your primary concern, generic orlistat 120mg delivers identical results at a lower price. Some patients prefer the branded Xenical for peace of mind, while others choose orlistat for better value. Both require the same prescription process and clinical assessment. Your choice depends on personal preference and budget - the weight management effect is the same.
Don't Forget Alli 60mg
For those considering a lower-strength option, Alli 60mg contains half the dose of prescription orlistat. At £26.09 for 4 weeks with EDM10, it's positioned between generic orlistat and Xenical pricing. However, the lower dose means it blocks a smaller proportion of dietary fat compared to the 120mg prescription versions.
How to Order Online
Complete our online clinical assessment where a UK-licensed prescriber reviews your medical history, BMI, and suitability for treatment. If approved, choose your preferred option - orlistat 120mg, Xenical 120mg, or Alli 60mg. All are dispensed by our GPhC-registered pharmacy in Leicester with discreet next day delivery. Use code EDM10 for 10% off your order.
What to Expect
Regardless of whether you choose orlistat or Xenical, both work by inhibiting lipase enzymes in your gut. Take one 120mg capsule with each main meal containing fat, up to three times daily. Both may cause similar gastrointestinal side effects, particularly if you eat high-fat meals. The key to success with either option is maintaining a reduced-calorie, lower-fat diet alongside treatment.


