Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
When deciding between orlistat 120mg and Xenical 120mg, understanding the facts helps you make the right choice. Both products contain exactly the same active ingredient—orlistat 120mg—at identical doses. They work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management alongside a reduced-calorie, lower-fat diet.
The main difference is manufacturer and price. Orlistat 120mg is the generic version, while Xenical 120mg is the branded product made by Roche. Clinically, they're equivalent—your body processes them identically.
Price Comparison: Generic vs Branded
Cost is where these products differ significantly. Our generic orlistat 120mg starts at £16.89 for 42 capsules (2-week supply), or £15.20 with discount code EDM10. Xenical 120mg costs £21.50 for the same quantity, or £19.35 with EDM10.
For a standard 4-week supply: orlistat costs £32.99 (£29.69 with EDM10), while Xenical costs £42.99 (£38.69 with EDM10). That's approximately £9 monthly savings with generic orlistat—over £100 annually if used long-term.
How to Use Both Products
Whether you choose orlistat or Xenical, usage instructions are identical. Take one 120mg capsule three times daily with each main meal containing fat. Take immediately before, during, or up to one hour after eating. If you miss a meal or eat a fat-free meal, skip that dose.
Both work best when your daily fat intake doesn't exceed 30% of calories (roughly 15g fat per meal). Higher fat meals increase gastrointestinal side effects significantly.
Consider Alli 60mg as an Alternative
If you prefer starting with lower-strength treatment, Alli 60mg offers half the dose of prescription orlistat. At £28.99 for 42 capsules (£26.09 with EDM10), it provides a gentler introduction to fat-blocking medication, typically with milder side effects.
Which Should You Choose?
Choose generic orlistat 120mg if cost-effectiveness is your priority—you'll get identical clinical benefits at lower prices. Choose Xenical 120mg if you prefer branded medication from an established pharmaceutical company. Both require prescription following clinical assessment by our UK-licensed prescribers.
Ready to start? Complete our online consultation today. Both products are dispensed by our GPhC-registered pharmacy with next day delivery across the UK. Use code EDM10 for 10% off your order.


