Same Effect, Different Price: Make Your Choice
Orlistat vs Xenical: The Key Differences
When comparing orlistat contraindications and choosing between generic orlistat 120mg and branded Xenical 120mg, the most important fact is this: both contain exactly the same active ingredient at identical doses. Clinically, they work in precisely the same way, blocking approximately one third of dietary fat absorption to support weight management alongside a reduced-calorie, lower-fat diet.
The primary difference lies in cost. Generic orlistat 120mg costs £32.99 for a 4-week supply (£29.69 with EDM10), while branded Xenical costs £42.99 (£38.69 with EDM10). Over a typical 12-week treatment course, choosing generic orlistat saves £33 compared to Xenical - that's over £100 annually for ongoing weight management.
Orlistat 120mg: Best Value Choice
Generic orlistat 120mg offers identical clinical effects to Xenical at the lowest possible price. Each capsule contains 120mg orlistat, taken three times daily with main meals containing fat. Following clinical assessment by our UK-licensed prescribers, you can order:
• 2 weeks (42 capsules): £16.89 → £15.20 with EDM10
• 4 weeks (84 capsules): £32.99 → £29.69 with EDM10
• 8 weeks (168 capsules): £63.99 → £57.59 with EDM10
• 12 weeks (252 capsules): £95.99 → £86.39 with EDM10
Xenical 120mg: The Branded Option
Some patients prefer branded Xenical 120mg, manufactured by Roche. While clinically equivalent to generic orlistat, Xenical represents the original branded formulation. Available following online clinical assessment:
• 2 weeks (42 capsules): £21.50 → £19.35 with EDM10
• 4 weeks (84 capsules): £42.99 → £38.69 with EDM10
• 8 weeks (168 capsules): £86.99 → £78.29 with EDM10
• 12 weeks (252 capsules): £128.99 → £116.09 with EDM10
Alli 60mg: Lower Strength Alternative
For those preferring a lower-strength option, Alli 60mg contains half the dose of prescription orlistat. While less potent than 120mg formulations, Alli may suit patients wanting to start with reduced strength. No prescription required, but still blocks a proportion of dietary fat absorption.
• 4 weeks (42 capsules): £28.99 → £26.09 with EDM10
• 8 weeks (84 capsules): £54.99 → £49.49 with EDM10
• 12 weeks (252 capsules): £129.99 → £116.99 with EDM10
Which Should You Choose?
Your choice between orlistat and Xenical depends primarily on budget and personal preference. Both have identical contraindications, require the same clinical assessment, and work through the same mechanism. Generic orlistat delivers maximum value, while Xenical offers brand recognition. Both are suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions, subject to prescriber approval.
Order Today with 10% Off
Complete your online clinical assessment now to determine suitability for orlistat 120mg or Xenical 120mg. Our UK-licensed prescribers review every application, ensuring appropriate treatment selection. Use code EDM10 for 10% off every order - new and returning customers. Next day delivery available across the UK from our GPhC-registered Leicester pharmacy. Start your weight management journey today.


