Orlistat vs Xenical: Make Your Choice Today
Orlistat vs Xenical: Clinical Equivalence
When choosing between orlistat and Xenical in the UK, it's essential to understand that both contain exactly the same active ingredient at the same dose - orlistat 120mg. Following clinical assessment by a UK-licensed prescriber, both work identically by inhibiting lipase enzymes in the gut, blocking approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through the digestive system, supporting weight management alongside a reduced-calorie, lower-fat diet.
Cost Comparison: Generic vs Branded
The primary difference between orlistat and Xenical is price. Generic orlistat 120mg costs £32.99 for a 4-week supply (84 capsules), reduced to £29.69 with discount code EDM10. Branded Xenical costs £42.99 for the same 4-week supply, reduced to £38.69 with EDM10. This represents savings of approximately £9 per month when choosing generic orlistat. For longer treatments, savings increase: 12-week supplies save over £30 when choosing orlistat (£86.39 with EDM10) versus Xenical (£116.09 with EDM10).
Does Orlistat Affect Periods?
Irregular menstruation is listed as an uncommon side effect of orlistat, potentially affecting up to 1 in 100 women taking either orlistat or Xenical. This occurs because orlistat may reduce absorption of fat-soluble vitamins including vitamin K, which plays a role in hormone regulation. If you experience significant menstrual changes while taking either medication, discuss this with your prescriber. Taking a daily multivitamin supplement (at bedtime, 2 hours after your last orlistat dose) may help maintain vitamin levels.
Which Should You Choose?
Your choice between orlistat and Xenical depends on personal preference and budget. Some patients prefer branded Xenical from manufacturer Roche, while others choose generic orlistat for value without compromising clinical effect. Both require the same dosing schedule: one capsule three times daily with each main meal containing fat. Both carry identical side effect profiles, predominantly gastrointestinal effects that reduce when keeping meals low in fat (approximately 15g fat per meal).
Alternative: Alli 60mg
For those preferring a lower-strength option, Alli 60mg provides half the dose of prescription orlistat. While clinically less potent, blocking a smaller proportion of dietary fat, Alli may suit those wanting to start with a gentler approach. Available in 4-week (£26.09 with EDM10), 8-week (£49.49 with EDM10) and 12-week supplies (£116.99 with EDM10).
Order Through EverydayMeds
Access either orlistat or Xenical through our GPhC-registered pharmacy following online clinical assessment. Complete our medical questionnaire for review by a UK-licensed prescriber. If treatment is deemed appropriate, your prescription will be dispensed and dispatched with next day delivery across the UK. Use code EDM10 for 10% off every order.
