Generic Orlistat or Branded Xenical: Making Your Choice
Orlistat vs Xenical: The Key Facts
When comparing orlistat 120mg capsules with Xenical 120mg, you're looking at clinically identical treatments. Both contain the same active ingredient (orlistat) at the same strength, work by the same mechanism, and require the same BMI eligibility criteria. The fundamental difference lies in price and manufacturer preference.
Generic orlistat 120mg offers excellent value at £32.99 for 84 capsules (£29.69 with EDM10), while branded Xenical costs £42.99 for the same quantity (£38.69 with EDM10). Over a 12-week treatment period, choosing generic orlistat saves approximately £27 compared to Xenical.
How Both Products Work
Whether you choose orlistat or Xenical, both work by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. This mechanism is identical between products - there's no clinical advantage to either formulation.
Both must be taken alongside a reduced-calorie, lower-fat diet and increased physical activity. The standard dosing is one 120mg capsule with each main meal containing fat, up to three capsules daily.
BMI Requirements and Eligibility
Both orlistat and Xenical have identical eligibility criteria. Following online clinical assessment, these prescription-only medicines may be suitable for adults with a BMI of 30 kg/m² or above, or BMI 28 kg/m² or above with weight-related health conditions such as type 2 diabetes or high blood pressure.
Our UK-licensed prescribers review each application individually, assessing whether treatment is appropriate based on your health questionnaire responses.
Pricing Comparison: Orlistat vs Xenical
Generic orlistat represents significant savings over branded Xenical. For a 4-week supply: orlistat costs £29.69 with EDM10 versus Xenical at £38.69. An 8-week supply costs £57.59 for orlistat compared to £78.29 for Xenical - saving £20.70. The 12-week option shows the greatest value difference: £86.39 for orlistat versus £116.09 for Xenical, saving nearly £30.
These competitive prices include the online prescription consultation, dispensing by our Leicester-based GPhC-registered pharmacy, and delivery to your address.
Consider Alli 60mg as an Alternative
For those preferring a lower-strength option, Alli 60mg provides half the dose of prescription orlistat. While less potent than 120mg formulations, Alli may suit those wanting to start with a gentler approach. Alli costs £49.49 for an 8-week supply with EDM10 discount.
Side Effects: Identical Between Products
Since orlistat and Xenical contain identical active ingredients, side effects are the same. Most are gastrointestinal and directly linked to dietary fat intake. Common effects include oily stools, increased bowel movement frequency, and abdominal discomfort. These can be minimised by keeping dietary fat low (approximately 15g per meal).
Order Today with 10% Discount
Ready to choose between orlistat and Xenical? Complete our online health questionnaire for clinical assessment by a UK-licensed prescriber. Both options are available with next day delivery across the UK. Use code EDM10 for 10% off every order, whether choosing cost-effective generic orlistat or branded Xenical. All medication is dispensed from our regulated Leicester pharmacy.


