Orlistat vs Xenical: Which Weight Loss Medicine to Buy?

pricing for mounjaro and wegovy weight loss

Choosing between generic orlistat 120mg and branded Xenical 120mg? Both contain identical active ingredients and work the same way, blocking approximately one third of dietary fat absorption. The key difference is price — orlistat costs £29.69 for 4 weeks versus Xenical at £38.69 (with EDM10 code). Both can be taken with antibiotics following prescriber guidance. Complete your online clinical assessment today to access either option through our GPhC-registered Leicester pharmacy, with next day delivery across the UK.

  • Same active ingredient — orlistat 120mg in both generic and Xenical
  • Save £9+ per month choosing generic over branded Xenical
  • Both suitable with antibiotics when prescribed together
  • 10% off every order with code EDM10 — new and returning customers
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Generic Orlistat vs Branded Xenical: Your Buying Guide

Orlistat 120mg vs Xenical 120mg: Identical Clinical Effect

When deciding between generic orlistat and branded Xenical, the most important fact is both contain exactly the same active ingredient at identical 120mg strength. Both work by blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in your digestive system. Clinically, there is no difference in effectiveness between the two options.

The Key Difference: Price Comparison

Generic orlistat offers significant cost savings compared to branded Xenical. For a 4-week supply (84 capsules), generic orlistat costs £32.99 (£29.69 with EDM10 discount) whilst Xenical costs £42.99 (£38.69 with EDM10). Over 12 weeks, you save over £30 choosing generic orlistat at £86.39 versus Xenical at £116.09. Both require the same prescription process and clinical assessment by our UK-licensed prescribers.

Can You Take Orlistat with Antibiotics?

Yes, orlistat can generally be taken alongside most antibiotics when prescribed together by a healthcare professional. Since orlistat works locally in your digestive system blocking fat absorption, it doesn't typically interact with systemic antibiotics. However, always inform your prescriber about any current medications during your online clinical assessment to ensure safe co-prescription.

Alli 60mg: The Lower-Strength Alternative

For those preferring a gentler starting approach, Alli 60mg offers half the strength of prescription orlistat. At £49.49 for 8 weeks (84 capsules with EDM10), Alli provides a lower-dose option with typically milder gastrointestinal side effects whilst still supporting weight management alongside a reduced-calorie, lower-fat diet.

Which Should You Choose?

Most patients choose generic orlistat for its cost-effectiveness, offering identical clinical benefits at lower cost. Some prefer branded Xenical for peace of mind with Roche's established branding. Your choice depends on personal preference and budget — both require the same online clinical assessment and are dispensed by our GPhC-registered pharmacy in Leicester with next day delivery.

How to Order: Simple Online Process

Complete our online health questionnaire covering your medical history, current medications including any antibiotics, and BMI information. Our UK-licensed prescriber reviews your assessment and, if clinically appropriate, issues your prescription. Choose from multiple pack sizes: 2-week (42 capsules), 4-week (84 capsules), 8-week (168 capsules), or 12-week (252 capsules) supplies. Use code EDM10 for 10% off your order.

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