Choose Your Orlistat: Generic vs Branded Comparison
Orlistat vs Xenical: The Key Differences
When comparing Orlistat 120mg and Xenical 120mg, the most important fact is they contain the identical active ingredient at exactly the same dose. Both work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management alongside a reduced-calorie, lower-fat diet. The primary difference is cost - generic Orlistat offers the same clinical effect at a lower price point.
Price Comparison: Generic vs Branded
At EverydayMeds, generic Orlistat 120mg costs £32.99 for 4 weeks (£29.69 with code EDM10), while branded Xenical costs £42.99 for the same supply (£38.69 with EDM10). Over 12 weeks, you could save £30 by choosing generic Orlistat at £86.39 versus Xenical at £116.09. Both options include the prescription fee and are dispensed by our GPhC-registered pharmacy in Leicester.
Clinical Effectiveness: Identical Results
Whether you choose generic Orlistat or branded Xenical, you receive the same 120mg dose of orlistat in each capsule. Both products work identically - inhibiting lipase enzymes to prevent approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your digestive system. Individual responses vary, but the clinical mechanism is identical regardless of whether you choose the generic or branded version.
Alli 60mg: The Lower-Strength Alternative
For those preferring a lower-dose starting point, Alli 60mg offers half the strength of prescription orlistat. Available from £26.09 for 4 weeks with code EDM10, Alli blocks a smaller proportion of dietary fat compared to the 120mg prescription versions. This lower dose may result in milder gastrointestinal side effects while still supporting weight management when used alongside dietary changes.
Which Should You Choose?
Many patients choose generic Orlistat 120mg for its cost-effectiveness, saving significantly compared to branded Xenical while receiving identical clinical benefits. Others prefer Xenical's established branding. Both require the same online clinical assessment by our UK-licensed prescribers and are suitable for adults with a BMI of 30 or above, or 28 or above with weight-related health concerns like type 2 diabetes or high blood pressure.
Ordering Process: Same for Both Options
Whether you choose Orlistat or Xenical, the process is identical. Complete our online health questionnaire, receive prescriber review, and have your chosen treatment dispensed and delivered discretely to your address. Both options qualify for next-day delivery across the UK, and the prescription fee is included in the price - no separate GP appointment required.
Managing Side Effects: Fat Intake Matters
Both Orlistat and Xenical may cause gastrointestinal side effects including oily stools, increased bowel frequency, and abdominal discomfort. These effects are directly linked to dietary fat intake - keeping meals to approximately 15g fat helps minimise side effects significantly. The lower-strength Alli 60mg typically causes milder side effects due to its reduced dose.


