Orlistat vs Xenical: Making Your Purchase Decision
Generic Orlistat 120mg vs Branded Xenical: The Facts
When comparing orlistat 120mg and Xenical 120mg, you're looking at two products containing exactly the same active ingredient at identical doses. Generic orlistat offers the same clinical effect as branded Xenical—both block approximately one third of dietary fat absorption through the same mechanism of action. The primary difference lies in cost, with generic orlistat providing significant savings without compromising effectiveness.
Price Comparison: Substantial Savings with Generic Orlistat
Generic orlistat 120mg costs £32.99 for four weeks (£29.69 with EDM10), while branded Xenical costs £42.99 (£38.69 with EDM10) for the same supply. Over a 12-week treatment course, choosing generic orlistat saves approximately £30 compared to Xenical. Both options include prescription assessment by UK-licensed prescribers and dispensing from our GPhC-registered pharmacy in Leicester.
Which Should You Choose?
Most patients choose generic orlistat for its value—clinically equivalent to Xenical at a lower price point. Some prefer branded Xenical for familiarity with the established name. Both work identically by inhibiting lipase enzymes in the gut, preventing approximately one third of dietary fat from being absorbed. Your choice typically comes down to budget and personal preference, as clinical outcomes remain the same.
Alli 60mg: The Lower-Strength Alternative
For those considering a gentler introduction to orlistat, Alli 60mg offers half the prescription dose. While less potent than 120mg formulations, Alli may suit patients preferring lower-strength treatment. Alli costs £26.09 for four weeks with EDM10—positioned between generic orlistat and Xenical pricing while providing reduced potency.
Online Prescription Process for Both Options
Whether choosing generic orlistat or branded Xenical, the prescription process remains identical. Complete our online health questionnaire for review by UK-licensed prescribers. Following clinical assessment, suitable patients receive their chosen treatment dispensed by our GPhC-registered pharmacy. Prescription costs are included—no separate GP appointment required.
Treatment Packs Available
Both orlistat and Xenical are available in multiple pack sizes: two-week starter packs, four-week supplies, eight-week courses, and 12-week treatment programmes. Generic orlistat starts from £15.20 for two weeks with EDM10, while Xenical begins at £19.35. Longer treatment courses offer better value per capsule across both options.


