Which Should You Choose: Generic Orlistat or Branded Xenical?
Orlistat vs Xenical: The Essential Facts
Both generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. They work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management alongside a reduced-calorie, lower-fat diet. The clinical effect is identical - the primary difference is cost.
Price Comparison: Significant Savings with Generic Orlistat
Generic orlistat offers substantial savings over Xenical. A 4-week supply (84 capsules) costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you save over £27 choosing generic orlistat at £86.39 versus Xenical at £116.09. Both are dispensed by the same GPhC-registered pharmacy with identical quality standards.
Why Some Patients Choose Xenical
Some patients prefer branded Xenical due to familiarity with the Roche brand name or previous positive experiences. However, generic orlistat undergoes the same rigorous MHRA approval process and contains precisely the same active ingredient at the same strength. Your prescriber can advise which option suits your needs and budget.
Consider Alli 60mg as a Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat. At £26.09 for a 4-week supply with EDM10, it offers a lower-strength starting point. However, the reduced dose means it blocks a smaller proportion of dietary fat compared to the 120mg prescription options.
Online Prescription Process
Both orlistat and Xenical require prescription following clinical assessment. Complete our online health questionnaire, reviewed by UK-licensed prescribers. If appropriate, your prescription is dispensed by our Leicester-based GPhC-registered pharmacy and delivered discreetly next day. Use code EDM10 for 10% off every order.
Making Your Decision
For most patients, generic orlistat 120mg provides the best value - identical clinical effect at significantly lower cost. However, the choice between generic and branded is personal. Both require the same dietary commitment and may cause similar gastrointestinal side effects when eating high-fat meals.


