Orlistat vs Xenical: Which Should You Buy?

pricing for mounjaro and wegovy weight loss

Both Orlistat 120mg and Xenical 120mg contain the same active ingredient and work identically to block approximately one third of dietary fat absorption. The key difference is cost - generic Orlistat starts from £15.20 (with EDM10), whilst branded Xenical costs from £19.35 (with EDM10). Following an online clinical assessment, our UK-licensed prescribers can determine which option suits you best. Both are prescription-only medicines dispensed by our GPhC-registered pharmacy with next day delivery. Use code EDM10 for 10% off every order.

  • Same clinical effect - both contain 120mg orlistat
  • Generic Orlistat saves approximately £9 per month vs Xenical
  • Both available from 2-week to 12-week supply options
  • Next day delivery with 10% discount code EDM10
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Should You Choose? Price vs Brand Comparison

Orlistat vs Xenical: The Key Differences

Orlistat 120mg and Xenical 120mg are clinically equivalent medications that work by blocking approximately one third of dietary fat absorption. The primary difference lies in cost and branding. Generic Orlistat offers the same active ingredient and identical clinical effect at a significantly lower price point.

Cost Comparison: Substantial Savings with Generic Orlistat

Generic Orlistat 120mg costs £29.69 for a 4-week supply (with EDM10), whilst branded Xenical costs £38.69 for the same period. Over a 12-week treatment course, you could save approximately £27 by choosing generic Orlistat (£86.39) versus Xenical (£116.09). Both options require a prescription following clinical assessment by our UK-licensed prescribers.

How Both Medications Work

Whether you choose Orlistat or Xenical, the mechanism remains identical. Both inhibit lipase enzymes in the gut to prevent approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through the body. This process can support weight management when used alongside a reduced-calorie, lower-fat diet and regular physical activity.

Alli 60mg: The Lower-Strength Alternative

For those preferring a lower-dose option, Alli 60mg contains half the strength of prescription orlistat. At £26.09 for a 4-week supply (with EDM10), Alli provides a gentler introduction to orlistat treatment, though with proportionally reduced clinical effect compared to the 120mg prescription versions.

Which Should You Buy?

Choose generic Orlistat 120mg if cost-effectiveness is your priority - you'll receive the same clinical benefit as Xenical at approximately 25% less cost. Some patients prefer branded Xenical for personal preference or familiarity with the Roche brand. Both options are subject to the same prescriber assessment and deliver identical weight management support when combined with appropriate dietary changes.

Getting Your Prescription Online

Both Orlistat and Xenical require prescription following an online clinical assessment. Complete our medical questionnaire, and a UK-licensed prescriber will review your eligibility. If appropriate, your prescription will be dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly with next day shipping. Use code EDM10 for 10% off your order.

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