Which Should You Choose: Generic or Branded?
Orlistat vs Xenical: Identical Effects, Different Prices
Both Orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses, working by blocking approximately one third of dietary fat absorption. The key difference lies in cost - generic Orlistat offers significant savings without compromising clinical effectiveness. Our 4-week supply of generic Orlistat costs £29.69 with code EDM10, compared to £38.69 for branded Xenical.
When to Take Orlistat or Xenical
Take one 120mg capsule three times daily with each main meal containing fat. The capsule should be taken immediately before, during, or up to one hour after eating. If you miss a meal or eat a fat-free meal, you can skip that dose. This timing ensures the medication works when your body is digesting dietary fat, maximising its fat-blocking effect.
Cost Comparison: Make an Informed Choice
Generic Orlistat from £15.20 (2-week supply) represents excellent value, while Xenical starts from £19.35 for the same period. For longer-term treatment, a 12-week supply of Orlistat costs £86.39 versus £116.09 for Xenical with EDM10 - saving nearly £30. Both options require the same clinical assessment and deliver identical results when used alongside a reduced-calorie, lower-fat diet.
Alli 60mg: The Lower-Strength Alternative
Alli contains half the dose of prescription-strength orlistat at 60mg per capsule. Starting from £26.09 for a 4-week supply with EDM10, it may be suitable for those preferring a gentler approach. However, the lower dose means it blocks a smaller proportion of dietary fat compared to prescription-strength options.
Your Online Prescription Journey
Complete our online health questionnaire covering your medical history, current medications, and BMI details. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Your chosen medication is then dispensed by our GPhC-registered pharmacy in Leicester and dispatched for next day delivery. The prescription is included in the price - no separate GP appointment needed.
Getting the Best Results
Whether you choose generic Orlistat or branded Xenical, success depends on keeping dietary fat intake low - approximately 15g per meal. Higher fat meals increase the likelihood of gastrointestinal side effects like oily stools and urgency. Both medications work best alongside a structured weight management programme including regular physical activity and behavioural support.


