Generic Orlistat vs Branded Xenical - Key Differences
Identical Clinical Effect, Different Prices
Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through your digestive system. Clinically, there is no difference in effectiveness between generic orlistat and branded Xenical - the key distinction lies in cost.
Orlistat 120mg Pricing (Generic)
Generic orlistat offers excellent value for identical clinical benefits. Our current pricing with EDM10 discount: 2 weeks (42 capsules) £15.20, 4 weeks (84 capsules) £29.69, 8 weeks (168 capsules) £57.59, and 12 weeks (252 capsules) £86.39. This represents significant monthly savings compared to branded alternatives whilst delivering the same fat-blocking mechanism.
Xenical 120mg Pricing (Branded)
Xenical, manufactured by Roche, commands premium pricing as the original branded version. With EDM10 discount: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, and 12 weeks £116.09. Some patients prefer branded Xenical for reassurance, though the active ingredient and clinical effect remain identical to generic orlistat.
Alli 60mg - Lower Strength Alternative
Alli offers half the dose of prescription-strength orlistat at 60mg per capsule. Available without prescription, it blocks a smaller proportion of dietary fat compared to 120mg formulations. Current Alli pricing with EDM10: 4 weeks £26.09, 8 weeks £49.49, 12 weeks £116.99. Suitable for those preferring a gentler starting approach to weight management.
Which Should You Choose?
Your choice between orlistat and Xenical depends primarily on budget preferences. If cost-effectiveness matters most, generic orlistat delivers identical results at lower prices. If you prefer branded medication reassurance, Xenical provides the same clinical benefits at premium pricing. Both require prescription following online clinical assessment by our UK-licensed prescribers.
Online Prescription Process
Complete our online health questionnaire covering medical history, current medications, and BMI information. A qualified UK prescriber reviews your submission and, where clinically appropriate, issues a prescription. Both orlistat and Xenical options are then dispensed by our GPhC-registered pharmacy in Leicester and dispatched for next-day delivery across the UK.
How to Use Either Option
Take one 120mg capsule three times daily with each main meal containing fat. If you miss a meal or eat a fat-free meal, skip that dose. Maximum three capsules daily. Both products work best alongside a reduced-calorie, lower-fat diet with approximately 15g fat per meal to minimise gastrointestinal side effects whilst maximising weight management support.


