Generic vs Branded: Which Should You Choose?
Why Weight Gain Occurs on Orlistat (Both Generic and Xenical)
Whether you're taking generic orlistat or branded Xenical, both contain exactly the same 120mg active ingredient. Weight gain isn't caused by choosing generic over branded — it typically occurs when dietary fat intake exceeds 15g per meal. Both products block approximately one third of dietary fat absorption, but only when used alongside a reduced-calorie, lower-fat diet.
Orlistat vs Xenical: Identical Clinical Effect
Generic orlistat 120mg and Xenical 120mg are clinically equivalent. Both work by inhibiting lipase enzymes in your digestive system to prevent absorption of approximately one third of dietary fat. The key difference is cost — generic orlistat costs £29.69 for 4 weeks vs Xenical at £38.69 with code EDM10, saving you over £100 annually.
Current UK Pricing Comparison
Generic orlistat offers significant savings: 4-week supply costs £29.69 (with EDM10) compared to Xenical at £38.69. For 12-week treatment, choose orlistat at £86.39 vs Xenical at £116.09 — that's £30 saved every three months. Both require the same online clinical assessment by our UK-licensed prescribers.
Alli 60mg: Lower-Strength Alternative
If you're experiencing side effects with 120mg strength, Alli 60mg provides half the dose at £49.49 for 8 weeks (with EDM10). While less potent than prescription-strength orlistat, it may suit those preferring a gentler starting point for weight management.
Addressing Weight Gain Issues
Weight gain on orlistat or Xenical often indicates dietary fat intake is too high. Both products require meals containing no more than 15g fat each to work effectively. High-fat meals not only reduce effectiveness but increase gastrointestinal side effects. Our prescribers can review your treatment approach during your online consultation.
Order Today with Next Day Delivery
Choose generic orlistat for best value or Xenical if you prefer the branded option — both dispensed by our GPhC-registered Leicester pharmacy. Complete your online clinical assessment today and get 10% off your first order with EDM10. Next day delivery available across the UK with discreet, tracked packaging.


