Why Am I Gaining Weight on Orlistat vs Xenical?

pricing for mounjaro and wegovy weight loss

Experiencing weight gain on orlistat? The issue isn't whether you choose generic orlistat or branded Xenical — both contain identical 120mg orlistat and work the same way. Weight gain may occur if dietary fat intake remains too high, reducing effectiveness. Generic orlistat costs £29.69 for 4 weeks vs Xenical at £38.69 (with EDM10). Both require the same low-fat diet approach. Our UK prescribers can review your treatment and recommend the most cost-effective option. Get 10% off either product with code EDM10.

  • Same active ingredient — orlistat 120mg in both generic and Xenical
  • Generic orlistat saves £9+ per month vs branded Xenical
  • Both require identical low-fat diet for effectiveness
  • UK prescriber review included — no separate GP appointment needed
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Our Pricing

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Generic vs Branded: Which Should You Choose?

Why Weight Gain Occurs on Orlistat (Both Generic and Xenical)

Whether you're taking generic orlistat or branded Xenical, both contain exactly the same 120mg active ingredient. Weight gain isn't caused by choosing generic over branded — it typically occurs when dietary fat intake exceeds 15g per meal. Both products block approximately one third of dietary fat absorption, but only when used alongside a reduced-calorie, lower-fat diet.

Orlistat vs Xenical: Identical Clinical Effect

Generic orlistat 120mg and Xenical 120mg are clinically equivalent. Both work by inhibiting lipase enzymes in your digestive system to prevent absorption of approximately one third of dietary fat. The key difference is cost — generic orlistat costs £29.69 for 4 weeks vs Xenical at £38.69 with code EDM10, saving you over £100 annually.

Current UK Pricing Comparison

Generic orlistat offers significant savings: 4-week supply costs £29.69 (with EDM10) compared to Xenical at £38.69. For 12-week treatment, choose orlistat at £86.39 vs Xenical at £116.09 — that's £30 saved every three months. Both require the same online clinical assessment by our UK-licensed prescribers.

Alli 60mg: Lower-Strength Alternative

If you're experiencing side effects with 120mg strength, Alli 60mg provides half the dose at £49.49 for 8 weeks (with EDM10). While less potent than prescription-strength orlistat, it may suit those preferring a gentler starting point for weight management.

Addressing Weight Gain Issues

Weight gain on orlistat or Xenical often indicates dietary fat intake is too high. Both products require meals containing no more than 15g fat each to work effectively. High-fat meals not only reduce effectiveness but increase gastrointestinal side effects. Our prescribers can review your treatment approach during your online consultation.

Order Today with Next Day Delivery

Choose generic orlistat for best value or Xenical if you prefer the branded option — both dispensed by our GPhC-registered Leicester pharmacy. Complete your online clinical assessment today and get 10% off your first order with EDM10. Next day delivery available across the UK with discreet, tracked packaging.

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