Compare Orlistat, Xenical & Alli: Make Your Choice
Orlistat vs Xenical: The Key Difference is Price
Both Orlistat 120mg and Xenical 120mg contain identical active ingredients at the same strength. The clinical effect is equivalent - both work by blocking approximately one third of dietary fat absorption. The primary difference lies in cost. Generic Orlistat 120mg costs £29.69 for a 4-week supply with EDM10, while branded Xenical costs £38.69 - a saving of £9 per month. Over a 12-week treatment period, choosing generic Orlistat saves £29.70 compared to Xenical.
Pricing Comparison: All Options
Orlistat 120mg (generic) offers the best value: 4-week supply £32.99 (£29.69 with EDM10), 8-week supply £63.99 (£57.59 with EDM10), 12-week supply £95.99 (£86.39 with EDM10). Xenical 120mg (branded): 4-week supply £42.99 (£38.69 with EDM10), 8-week supply £86.99 (£78.29 with EDM10), 12-week supply £128.99 (£116.09 with EDM10). Alli 60mg provides a lower-strength option at £54.99 for 8 weeks (£49.49 with EDM10).
Which Strength Should You Choose?
Orlistat and Xenical at 120mg are prescription-only medicines requiring clinical assessment by a UK-licensed prescriber. They may be suitable for adults with BMI 30kg/m² or above, or BMI 28kg/m² with weight-related health conditions. Alli at 60mg offers half the strength for those preferring a gentler approach. All work by the same mechanism - inhibiting lipase enzymes to reduce dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
Same Quality Standards, Different Prices
Whether you choose generic Orlistat or branded Xenical, both are dispensed by our GPhC-registered pharmacy in Leicester following the same rigorous quality standards. All products are sourced through MHRA-regulated supply chains. The active ingredient orlistat works identically in both formulations - blocking approximately one third of dietary fat from each meal. Your choice often comes down to budget preference and brand familiarity.
Start Your Assessment Today
Complete our online clinical assessment to determine which option may be most suitable for your individual circumstances. Our UK-licensed prescribers review each case individually, ensuring appropriate treatment selection. Following prescriber approval, your chosen medication is dispensed and dispatched with next-day delivery across the UK. Use code EDM10 for 10% off every order, whether you choose cost-effective Orlistat, branded Xenical, or lower-strength Alli.


