Orlistat vs Xenical: Compare Prices and Make Your Choice
Will Orlistat Show Up on a Drug Test?
Neither orlistat nor Xenical typically appear on standard drug tests. Both medications work by blocking lipase enzymes locally in the gut to prevent absorption of approximately one third of dietary fat. Unlike stimulant-based weight loss medications that affect the brain, orlistat is not absorbed into the bloodstream in significant amounts, making it unlikely to trigger positive results on workplace or medical drug screenings. However, always inform healthcare professionals about any prescription medications you're taking before drug testing.
Generic Orlistat vs Branded Xenical: The Key Differences
The primary difference between orlistat 120mg and Xenical 120mg is price, not clinical effect. Both contain identical amounts of the same active ingredient and work in exactly the same way. Generic orlistat costs £29.69 for 4 weeks with EDM10, whilst Xenical costs £38.69 - saving you over £9 monthly. Xenical is manufactured by Roche as the original branded version, but generic orlistat offers clinically equivalent results at better value. Some patients prefer branded medication, whilst others choose generic orlistat for the substantial cost savings.
Current Orlistat and Xenical Prices at EverydayMeds
Our GPhC-registered pharmacy offers competitive pricing on both options. Generic orlistat 120mg: 2 weeks £15.20, 4 weeks £29.69, 8 weeks £57.59, 12 weeks £86.39 (all with EDM10). Branded Xenical 120mg: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 (with EDM10). We also stock Alli 60mg as a lower-strength alternative from £26.09 for 4 weeks. All prices include prescription costs - no separate GP fees required.
How Both Orlistat and Xenical Work
Whether you choose generic orlistat or branded Xenical, both work identically by inhibiting lipase enzymes in your digestive system. This prevents approximately one third of dietary fat from being absorbed, with unabsorbed fat passing naturally through your body. Both must be used alongside a reduced-calorie, lower-fat diet and regular physical activity. Take one 120mg capsule with each main meal containing fat, up to three times daily. The medication works best when meals contain no more than 15g fat each to minimise gastrointestinal side effects.
Getting Your Prescription Online
Both orlistat and Xenical require prescription following clinical assessment. Our online service allows you to complete a medical questionnaire reviewed by UK-licensed prescribers. If treatment is deemed suitable, your prescription is dispensed by our Leicester-based pharmacy and delivered discreetly with next day delivery available. The process typically takes 24-48 hours from consultation to delivery, much faster than booking GP appointments. Use code EDM10 for 10% off your order.
Which Should You Choose?
If you want the most cost-effective option with identical clinical benefits, generic orlistat 120mg is the smart choice, saving you over £100 annually compared to Xenical. If you prefer branded medication from the original manufacturer, Xenical remains available at competitive prices. Both are equally effective for weight management when used correctly. For those preferring a gentler starting dose, Alli 60mg offers half the strength with typically milder side effects. Your prescriber will help determine the most suitable option during your clinical assessment.


