Compare Orlistat vs Xenical: Make Your Choice
Orlistat vs Xenical: The Key Differences
Both Orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses, making them clinically equivalent treatments. The primary difference lies in cost - generic Orlistat offers substantial savings compared to branded Xenical. A 4-week supply of Orlistat costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10). Over 12 weeks, you could save over £30 by choosing generic Orlistat at £95.99 versus Xenical at £128.99.
How Both Treatments Work
Whether you choose Orlistat or Xenical, the mechanism remains identical. Both work by blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in the digestive system. This unabsorbed fat passes naturally through the body, supporting weight management when used alongside a reduced-calorie, lower-fat diet. Neither affects carbohydrates or proteins - only dietary fat absorption is reduced.
Which Should You Choose?
Your choice between Orlistat and Xenical often comes down to personal preference and budget. Generic Orlistat provides excellent value whilst delivering the same clinical benefits as branded Xenical. Some patients prefer Xenical's established branding, whilst others choose Orlistat for cost-effectiveness. Both require the same prescription process and clinical assessment by qualified UK-licensed prescribers through our GPhC-registered pharmacy.
Alli 60mg: The Lower-Strength Alternative
Consider Alli 60mg if you prefer starting with a lower-strength option. At half the dose of prescription-strength treatments, Alli may be suitable for those wanting a gentler introduction to orlistat therapy. Available from £28.99 (£26.09 with EDM10) for 4 weeks, Alli blocks a smaller proportion of dietary fat with typically milder gastrointestinal effects.
Complete Pricing Comparison
Orlistat 120mg pricing: 2 weeks £16.89 (£15.20 EDM10), 4 weeks £32.99 (£29.69 EDM10), 8 weeks £63.99 (£57.59 EDM10), 12 weeks £95.99 (£86.39 EDM10). Xenical 120mg pricing: 2 weeks £21.50 (£19.35 EDM10), 4 weeks £42.99 (£38.69 EDM10), 8 weeks £86.99 (£78.29 EDM10), 12 weeks £128.99 (£116.09 EDM10). All prices include prescription following successful clinical assessment.
Order Process and Delivery
Both treatments follow the same streamlined ordering process. Complete our online clinical questionnaire, receive prescriber review from UK-licensed healthcare professionals, and get dispensed medication delivered discreetly to your address. Subject to clinical assessment and prescriber approval, both Orlistat and Xenical are dispatched from our Leicester-based GPhC-registered pharmacy with next-day delivery available across the UK. Use code EDM10 for 10% off your order.


