Orlistat vs Xenical: Which Should You Choose?
Understanding Orlistat vs Xenical
Orlistat and Xenical both contain exactly the same active ingredient — orlistat 120mg. The clinical effect is identical: both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Orlistat is the generic version, whilst Xenical is the branded product manufactured by Roche. Following online clinical assessment, UK-licensed prescribers can prescribe either option based on your preference and budget.
Price Comparison: Orlistat vs Xenical
The main difference between orlistat and Xenical is cost. Generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), saving approximately £9 per month compared to Xenical at £42.99 (£38.69 with EDM10). For 12-week supplies, orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10). Both prices include the prescription consultation with no additional GP fees required.
Clinical Effectiveness: Identical Results
Both orlistat 120mg and Xenical 120mg provide the same weight management support. Each capsule contains identical orlistat doses and works through the same mechanism — inhibiting lipase enzymes in the gut to reduce dietary fat absorption by approximately one third. Individual responses vary, but both products may help support weight reduction when used as part of a structured weight management programme alongside dietary and lifestyle changes.
Alli 60mg: Lower-Strength Alternative
For those preferring a lower-strength option, Alli contains 60mg orlistat — half the prescription dose. Alli costs £28.99 for 4 weeks (£26.09 with EDM10) and typically causes milder gastrointestinal side effects due to the reduced dose. However, the weight management effect is correspondingly lower than the 120mg prescription-strength versions.
Order Orlistat or Xenical Online
Both orlistat and Xenical require prescription following online clinical assessment by qualified UK-licensed prescribers. Complete our medical questionnaire covering your weight management goals, current medications, and health history. If treatment is deemed appropriate, your prescription will be dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available.
Which Treatment Should You Choose?
Choose generic orlistat 120mg for maximum value — clinically identical to Xenical but significantly more affordable. Choose Xenical 120mg if you prefer the branded option from Roche. Choose Alli 60mg for a lower-strength starting point. All options require commitment to a reduced-calorie, lower-fat diet and regular physical activity. Apply code EDM10 at checkout for 10% off your order.


